Structural and Evolutionary Genomics: Natural Selection in Genome Evolution - Rilegato

Bernardi, Giorgio

 
9780444512550: Structural and Evolutionary Genomics: Natural Selection in Genome Evolution
Rilegato
ISBN 10: 0444512551 ISBN 13: 9780444512550
Casa editrice: Elsevier Science Ltd, 2004

Sinossi

Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics. As the subtitle indicates the book discusses the fundamental importance of natural selection in shaping genomes. In terms of numbers, neutral and nearly neutral mutations represent most mutations, but a regional control is exerted by natural selection (essentially negative or purifying selection). A neo-selectionist model is proposed for genome evolution.

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Product Description

xiv 434p hardback with dustjacket, many illustrations (in colour), nice fresh clean copy with author inscription addressed to Sir Richard Keynes

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Editore
Elsevier Science Ltd
Data di pubblicazione
2004
Lingua
Inglese
ISBN 10 
0444512551
ISBN 13 
9780444512550
Rilegatura
Copertina rigida
Numero di pagine
342
Contatto del produttore
non disponibile
Persona responsabile
Barbara Criscuolo
b.criscuolo@lswr.it

Via Spadolini, 7
Milano
20141
Italia