Comparative Toxicogenomics: Volume 2 - Rilegato

Rilegato

ISBN 10: 0444532749 ISBN 13: 9780444532749

Casa editrice: Elsevier Science Ltd, 2008

Riassunto

Toxicogenomics analyses the activity of a particular toxin or chemical substance on living tissue based upon a profiling of its known effects on genetic material. Toxicogenomics is important because it may enhance understanding of mechanisms of toxicity, cellular defence systems, and drug action. If this technique is proven to work, it could be used in a similar way for toxicology and toxin-determination to DNA-testing in the forensic identification of individuals.

Comparative Toxicogenomics provides a timely overview of current achievements and future areas of development including a review of some of the first really fruitful studies made in this area.

* Provides a review of some of the first really fruitful studies made in this area.

* Covers different organisms ranging from humans to model species and environmental sentinels so researchers can see how this technique has been used across different organisms and compare the results of each.

* The chapters transect research interests from identification of toxic action to environmental monitoring providing a broad view of the area increasing its attractiveness to researchers working in a variety of specialties.

Su questo libro

Dalla quarta di copertina

Functional genomics has come of age. No longer is it an adventure for the avant garde scientist, but it has become an increasingly standardized mainstream tool accessible to any modern biological laboratory. Toxicogenomics studies are now generating an avalanche of data that, with the aid of established informatics methodology, is being translated into biologically meaningful information.

This is enabling us to start harvesting the benefits from years of investment in terms of technology, time, and (of course) money. It is therefore timely to bring together leading toxicologists with a wide variety of scientific aims in this book to demonstrate how microarray technology can be successfully applied to different research areas. This book transects biology from bacteria to human, from ecologically relevant sentinel organisms to well-characterized model species, and represents the full toxicogenomics arena from exploratory "blue sky" science to the prospects for incorporation into regulatory frameworks.

Dettagli dell'edizione

• Editore: Elsevier Science Ltd
• Data di pubblicazione: 2008
• Lingua: Inglese
• ISBN 10: 0444532749
• ISBN 13: 9780444532749
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 321
• Redattore: Hogstrand Christer, Kille Pete
• Contatto del produttore: non disponibile
• Persona responsabile: LSWR Group; b.criscuolo@lswr.it; ; Via Spadolini, 7; Milano; Italia