Role of the Sarcoplasmic Reticulum in Smooth Muscle - Rilegato

 
9780470844793: Role of the Sarcoplasmic Reticulum in Smooth Muscle
Rilegato
ISBN 10: 0470844795 ISBN 13: 9780470844793
Casa editrice: John Wiley & Sons Inc, 2002

Sinossi

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a central role in smooth muscle function, increasing in concentration for contraction and decreasing for relaxation. Calcium entry into the cell is facilitated by the sarcoplasmic reticulum (SR).

This book explores the latest research on the role of the sarcoplasmic reticulum (SR) in smooth muscle function. It examines the control and modulation of the SR and how this may vary among smooth muscle types. Potential therapeutic implications are also discussed.

  • Discusses new and exciting work in this area and identifies promising new research directions.
  • Considers the advances in this relatively unexplored field, offering new insights into the role of the SR muscle.
  • Brings together contributions from key workers, both in basic and clinical science, whose studies range from physiological to pathological and molecular to whole animal.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Informazioni sull?autore

Derek J. Chadwick and Jamie A. Goode are editors for Role of the Sarcoplasmic Reticulum in Smooth Muscle and other scientific titles.

Dalla quarta di copertina

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a central role in its function, increasing in concentration for contraction and decreasing for relaxation. The source of calcium is through entry across the surface membrane and release from the sarcoplasmic reticulum (SR). However, recent data have challenged the view that the SR is simply a source and sink of calcium ions. Indeed, the SR probably also acts to limit contraction, via ion channel-based feedback mechanisms.

This book explores the latest research on the role of the SR in smooth muscle function. Separate chapters examine the relationship between calcium release and inhibition and/or promotion of contraction, the control and modulation of the SR in smooth muscle and the extent to which the SR may vary between smooth muscles. Potential therapeutic implications of this research are discussed.

With contributions from an international group of experts, ranging from clinicians to molecular biologists, this book discusses new and exciting work in this area and identifies promising new research directions.

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
John Wiley & Sons Inc
Data di pubblicazione
2002
Lingua
Inglese
ISBN 10 
0470844795
ISBN 13 
9780470844793
Rilegatura
Copertina rigida
Numero di pagine
296
Redattore
Chadwick Derek, Goode Jamie
Contatto del produttore
WROX
https://www.wiley.com/en-us

111 River Street
Hoboken
NJ
7030
U.S.A.
Persona responsabile
non disponibile

Altre edizioni note dello stesso titolo

9780470853054: Role of the Sarcoplasmic Reticulum in Smooth Muscle, No. 246

Edizione in evidenza

ISBN 10:  0470853050 ISBN 13:  9780470853054
Casa editrice: John Wiley & Sons, 2003
Brossura