Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells.
Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results.
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Areles Molleman is the author of Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology, published by Wiley.
Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology is a concise introduction to the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the fundamentals of the subject, platforms, equipment and environmental control. This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this important technique, including an overview of membrane biophysics, standard experimental design, data analysis and technical concerns.
Aimed at novice and intermediate researchers within neurobiology laboratories, this text will also be of interest to people new to this technique, in universities and research labs as well as research technicians. A useful reference for undergraduates specialising in neurophysiology, neuropharmacology and applied physiology.
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