Mobile genetic elements are responsible for many previously little-understood phenomena. This collection of review articles surveyss some of the most recent and exciting advances in our understanding of the mechanisms, regulation, and consequences of genetic transposition of these elements. It surveys transposition in a wide range of organisms, both prokaryotic and eukaryotic. In addition, the possible evolutionary consequences of transposition are given full consideration. The whole area of transposition is generating considerable interest and excitement and this up-to-date and timely volume will have broad appeal.
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"This volume is of high quality and should be presented in libraries." Quarterly Review of Biology
Editors' preface; 1. Introduction N. Datta; Part I. Prokaryotic Systems: 2. Genome flux in Streptomyces coelicolor and other streptomycetes and its possible relevance to the evolution of mobile antibiotic resistance determinants K. F. Chater, D. J. Henderson, M. J. Bibb and D. A. Hopwood; 3. Transposition in Streptococcus: structural and genetic properties of the conjugative transposon Tn 916 D. B. Clewell, E. Senghas, J. M. Jones, S. E. Flannagan, M. Yamamoto and C. Gawron-Burke; 4. Transposable elements in Staphylococcus E. Murphy; 5. Multiple correlations among insertion sequences in the genome of natural isolates of Escherichia coli D. L. Hartl and S. A. Sawyer; 6. Mechanism and regulation of transposition D. E. Berg, T. Kazic, S. H. Phadnis, K. W. Dodson and J. K. Lodge; 7. Mechanism of the DNA strand transfer step in transposition of Mu DNA R. Craigie, M. Mizuuchi, K. Adzuma and K. Mizuuchi; 8. Site-specific recombination by the y d resolvase G. F. Hatfull, J. J. Salvo, E. E. Falvey, V. Rimphanitchayakit and N. D. F. Grindley; 9.Site-specific inversion in bacteriophage Mu P. van de Putte; 10. Phase and antigenic variation by DNA rearrangements in procaryotes T. F. Meyer and R. Haas; Part II. Eukaryotic Systems: 11. The yeast retrotransposon Ty and related elements A. J. Kingsman, S. E. Adams, S. M. Fulton, M. H. Malim, P. D. Rathjen, W. Wilson and S. M. Kingsman; 12. Structure and evolution of retroviruses with homology to the transposable intracisternal A-particle elements of mice E. L. Kuff and K. K. Lueders; 13. I-factors in Drosophila melanogaster and similar elements in other eukaryotes D. J. Finnegan; 14. P elements in Drosophila melanogaster: their biology and use as vector systems D. C. Rio; 15. DNA recombinations and transposition in trypanosomes E. Pays; 16. Transposons and retrotransposons in plants: analysis and biological relevance Z. Schwarz-Sommer and H. Saedler; 17. Transfer of T-DNA from Agrobacterium into plants J. Schell; Index.
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