This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which constitute metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. Algorithms are developed which can be implemented in computer programs for the derivation of equations. The treatment of steady-state enzyme kinetics is extended to allosteric enzymes and subunit interactions in polymeric enzymes. Principles are presented which provide for mathematical analysis of the control of multi-enzyme systems. Problems are included at the end of each chapter and their solutions are found at the end of the book. This book will be a useful text for advanced undergraduates and graduate students taking courses in enzyme chemistry and enzyme kinetics.
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"Currently, very few introductions to enzyme kinetics are available; this book could serve either as a text for a course in enqyme kinetics or as a reference for those needing an introduction to steady state enzyme kinetics. Definitely recommended." L.M. Prescott, Choice
Preface; Part I. Basic Steady State Enzyme Kinetics: 1. Derivation of a rate equation; 2. A closer look at the basic assumptions; 3. Enzyme inhibition; 4. Reversible enzyme-catalyzed reactions; Part II. Enzyme Reaction Sequence: 5. Multi-reactant enzymic reactions; 6. Analysis of multi-reactant enzyme kinetics; 7. Prediction of reaction sequence; 8. Enzyme-catalyzed isotopic exchange; 9. Kinetic isotope effect on steady state parameters; 10. The effect of pH on enzyme kinetics; Part III. Non-Hyperbolic Enzyme Kinetics: 11. The causes of non-hyperbolic enzyme kinetics; 12. Analysis of non-hyperbolic enzyme kinetics; 13. The effect of subunit interactions on enzyme kinetics; Part IV. Control of Multi-Enzyme Systems: 14. Control of linear multi-enzyme systems; 15. Control of branched multi-enzyme systems; 16. Biochemical systems theory; Part V. Solutions To Problems: Author index; Subject index.
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Hardcover. Condizione: new. Hardcover. This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book. This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which comprise metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9780521445009
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Condizione: New. This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which comprise metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. Num Pages: 260 pages, 101 line drawings. BIC Classification: PNNP; PSBZ; PSD. Category: (P) Professional & Vocational; (U) Tertiary Education (US: College). Dimension: 228 x 152 x 19. Weight in Grams: 550. . 1995. hardcover. . . . . Codice articolo V9780521445009
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Hardcover. Condizione: new. Hardcover. This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book. This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which comprise metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Codice articolo 9780521445009
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which comprise metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms . Codice articolo 446935795
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