Protein Targeting and Translocation - Brossura

Brossura

ISBN 10: 0691607397 ISBN 13: 9780691607399

Casa editrice: Princeton Univ Pr, 2014

Riassunto

Protein targeting is a fast-moving field that has encompassed areas from biophysics to molecular biology to try to gain insight into how proteins are directed to their final functional location and how such macromolecules are able to cross semi-permeable membrane barriers during their journey. This text reviews our current state of knowledge regarding the interaction of proteins at the membrane interface and the assembly of proteins into biological membranes, before proceeding to look at targeting pathways in both prokaryotic and eukaryotic systems. The reviews have been written by some of the leading researchers in the field, with contributions from around the world and with more than 1,800 references. The text is aimed at graduate students and at researchers with an interest in protein targeting, but may also be of use to final-year undergraduates.

Originally published in 1999.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Su questo libro

Contenuti

	Preface
	Abbreviations
	Membrane interactions
1	Biophysics of the membrane interface and its involvement in protein targeting and translocation	1
2	Amphiphilic [alpha]-helices and lipid interactions	19
3	Signal sequences: initiators of protein translocation	37
4	Determinants of membrane protein topology and membrane anchoring	49
5	Insertion of single- and multi-spanning proteins into the bacterial cytoplasmic membrane	67
6	Prokaryotic protein translocation	85
7	Protein traffic from the cytosol to the outer membrane of Escherichia coli	105
8	sec-dependent prokaryotic protein secretion	121
9	Targeting and assembly of fimbriae	143
10	Targeting to and translocation across the endoplasmic reticulum membrane	169
11	Protein localization to the endoplasmic reticulum and Golgi complex	193
12	Import and export of proteins at the nucleus	213
13	Mitochondrial targeting and import	231
14	Translocation of proteins into and across the thylakoid membrane	249
15	Principles of peroxisomal protein sorting and assembly	259
16	Targeting of glyoxysomal proteins	273
	Subject index	287

Dettagli dell'edizione

• Editore: Princeton Univ Pr
• Data di pubblicazione: 2014
• Lingua: Inglese
• ISBN 10: 0691607397
• ISBN 13: 9780691607399
• Rilegatura: Copertina flessibile
• Numero di pagine: 304
• Redattore: Phoenix D. A.
• Contatto del produttore: non disponibile
• Persona responsabile: Buchpark GmbH; gpsr@buchpark.de; ; Krügerweg 1; Trebbin; Brandenburg; 14959; Germania