Articoli correlati a Handbook of Downstream Processing
Sinossi
This handbook focuses on the operations which promise to produce genetically engineered materials for use in producing such end products as: enzymes, antibiotics, hormones, peptides, polypeptides, proteins, amino acids, veterinary drugs, steroids, herbicides, growth promoters, liposomes, diagnostic kits for infectious diseases, and many other materials that focus on pharmaceutical needs. The information in this volume should be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces such issues as: should the process be batch or continuous, or a combination of both?; how should the optimum process design be developed?; should one employ a new revolutionary separation which could be potentially difficult to validate, or use accepted technology which involves less risk?; should the process be run with ingredients formulated from water for injection, deionized water, or even filtered tap water?; should any of the separations be run in cold rooms or in glycol jacketed lines to minimize microbial growth where sterilization is not possible?
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Recensione
`... the book offers a great deal of useful information for readers.'
Angewandte Chemie
Contenuti
Preface. Lysing. Filtration. Pharmaceutical applications of liquid-liquid extractions. Affinity adsorption. Membrane separations in downstream processing. Electrodialysis. Large-scale column chromatography: a GMP manufacturing perspective. Product recovery and purification via precipitation and crystallization. Lyophilization. Drying in the pharmaceutical and biotech fields. Sterilization in the pharmaceutical and biotechnology industries. Pharmaceutical packaging operations. Clean-in-place and sterilize-in-place systems. Controls and automation for biotech and pharmaceutical industries. Agitation in fermenters and bioreactors. Distillation in the pharmaceutical industry. High purity water. The facility design process. Clean room testing and certification. Regulatory considerations. Validation. Project execution for the design and construction of a biotech facility. Bulk pharmaceutical and biopharmaceutical plant design considerations. Optimization of protein recovery using computer-aided process design tools. Off-site construction: application to the pharmaceutical and biotech industries. Wastewater treatment in the pharmaceutical industry. References. Index.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of mi. Codice articolo 5959488
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Handbook of Downstream Processing
Editore:
Springer Netherlands Okt 1996, 1996
ISBN 10: 0751403644
ISBN 13: 9780751403640
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The last two decades have seen a phenomenal growth of the field of genetic or biochemical engineering and have witnessed the development and ultimately marketing of a variety of products-typically through the manipulation and growth of different types of microorganisms, followed by the recovery and purification of the associated products. The engineers and biotechnologists who are involved in the full-scale process design of such facilities must be familiar with the variety of unit operations and equipment and the applicable regulatory requirements. This book describes current commercial practice and will be useful to those engineers working in this field in the design, construction and operation of pharmaceutical and biotechnology plants. It will be of help to the chemical or pharmaceutical engineer who is developing a plant design and who faces issues such as: Should the process be batch or continuous or a combination of batch and continuous How should the optimum process design be developed Should one employ a new revolutionary separation which could be potentially difficult to validate or use accepted technology which involves less risk Should the process be run with ingredients formulated from water for injection, deionized water, or even filtered tap water Should any of the separations be run in cold rooms or in glycol jacketed lines to minimize microbial growth where sterilization is not possible Should the process equipment and lines be designed to be sterilized in-place, cleaned-in-place, or should every piece be broken down, cleaned and autoclaved after every turn 756 pp. Englisch. Codice articolo 9780751403640
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Buch. Condizione: Neu. Handbook of Downstream Processing | E. Goldberg | Buch | Einband - fest (Hardcover) | Englisch | 1996 | Springer Netherland | EAN 9780751403640 | Verantwortliche Person für die EU: Springer Netherlands, Haberstr. 7, 69126 Heidelberg, buchhandel-buch[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 102154062
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Condizione: New. In English. Codice articolo ria9780751403640_new
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Condizione: New. "Handbook of Downstream Processing". Editor(s): Goldberg, Elliott. Num Pages: 720 pages, biography. BIC Classification: TCB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 234 x 156 x 40. Weight in Grams: 2670. . 1996. Hardback. . . . . Codice articolo V9780751403640
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