This study focuses on the evolving linear structure of the genome, from organelles and prokaryotes through to the multichromosomal nuclear genomes of plants and animals, based on modern genome map and sequence data. The collection brings together the diverse range of combinatorial optimization and probabilistic modeling techniques for analyzing genome rearrangements in the context of clinical cytogenetics, molecular genetics, population biology, microbial genomics, and the domesticated plant and animal genome projects. It critically compares functional and neutral conceptions of genome rearrangement and represents a concerted attack on the modeling and analytical problems associated with gene and genome duplication and with multigene families.
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Preface. Foreword; W.F. Doolittle. Introduction. Comparative Genomics; D. Sankoff, J.H. Nadeau. 1. Mechanisms. Cytogenetics, Molecular Genetics, Population Genetics. 2. Organelles: Mitochondria and Chloroplast. Rearrangements in Small Genomes. 3. Combinatorial Algorithms. A New Set of Problems for a New Kind of Data. 4. Prokaryotes. Genome Scrambling versus Functional Clustering. 5. Statistics. The Quantification of Comparative Mapping. 6. Nuclear Genomes. Evolutionary Inference from Comparative Mapping. 7. Gene and Genome Duplication and Multi-gene Families. How Can Duplication by Analyzed?
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A comprehensive account of genomic rearrangement, focusing on the mechanisms of inversion, translocation, gene and genome duplication and gene transfer and on the patterns that result from them in comparative maps. Includes analyses of genomic sequences . Codice articolo 5969535
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Buch. Condizione: Neu. Comparative Genomics | Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families | J. H. Nadeau (u. a.) | Buch | xiii | Englisch | 2000 | Springer Netherland | EAN 9780792365839 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 102563173
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Condizione: New. Provides a comprehensive account of genomic rearrangement, focusing on the mechanisms of inversion, translocation, gene and genome duplication and gene transfer and on the patterns that result from them in comparative maps. This book showcases a variety of algorithmic and statistical approaches to rearrangement and map data. Editor(s): Sankoff, David; Nadeau, Joseph H. Series: Computational Biology. Num Pages: 570 pages, biography. BIC Classification: PSAK1. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 234 x 156 x 31. Weight in Grams: 978. . 2000. Hardback. . . . . Codice articolo V9780792365839
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