This volume focuses on the transient gene expression technologies for recombinant protein production and gene therapy. Topics covered range from the use of baculovirus, adenovirus, adeno-associated virus and alphavirus vectors in biopharmaceutical, genomics and gene delivery research, to large-scale transfection of plasmid DNA into cultured cells for bioreactor applications. The book illuminates all the scientific and technological issues involved in the research, development, production, and human use of viral and non-viral vectors for in vitro and in vivo expression of recombinant proteins, thus making it an useful reference for cell culture technologists, virologists, and scientists interested in gene therapy.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Application of Recombinant Baculoviruses in Biopharmaceutical Research; T.A. Kost, et al. Engineering Post-Translational Processing of Recombinant Proteins Produced in Insect Cell Culture; E. Ailor, M.J. Betenbaugh. A Guide to Successful Scale-Up of the Baculovirus Expression System; C. Mannix, R.F. Jarman. Transient Gene Expression in Mammalian Cells Based on the Calcium Phosphate Transfection Method; M. Jordan. Adenovirus Vectors in Functional Genomics; W. Oualikene, B. Massie. Adeno-Associated Virus: A Promising Tool for Gene Delivery; A.M. Douar. Alpha Virus Vectors: Highly Efficient Systems for Transient Gene Expression; C. Smerdou, P. Liljeström. Transient Expression in Mammalian Cells: Applications and Perspectives; A.R. Bernard. Subject Index.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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