Mechanics and Energetics of the Myocardium: 10 - Rilegato

Holubarsch, Christian; Schroder, M. Philipp; Mollmann, Helge

 
9780792375708: Mechanics and Energetics of the Myocardium: 10

Sinossi

During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure.
It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals.
Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.

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Contenuti

Preface. 1. Historical Aspects: The Frank-Starling Mechanism. 2. The Myothermal Method: Historical and Personal Aspects. 3. Papillary Muscle Experiments. 4. The Myothermal Approach. 5. Skinned Fiber Experiments. 6. The Frequency Response Method. 7. Single Cell Experiments. 8. Diastolic Compliance. 9. The PVA-concept. 10. Human Studies in vivo.

Product Description

Book by Holubarsch Christian JF

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Altre edizioni note dello stesso titolo

9781461352846: Mechanics and Energetics of the Myocardium: 10

Edizione in evidenza

ISBN 10:  1461352843 ISBN 13:  9781461352846
Casa editrice: Springer, 2012
Brossura