Sinossi
In order to help people make their own assessment of a published manuscript or the risk assigned to a family member, Bridge (medical genetics and pathology, U. of Calgary) explains the fundamentals of how geneticists start with laboratory results and end up with a number representing genetic risk. He avoids abstract equations in favor of worked examples using numbers instead of symbols. Without trying to provide an example of every possible scenario, he offers principles and techniques by which readers can make their own adaptations. His revisions from the 1994 edition include a new discussions of haploid risk calculation, cancer-specific testing, and DNA polymorphisms to test paternity and analyze zygosity. Includes a glossary without pronunciation. Annotation c. by Book News, Inc., Portland, Or.
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Recensione
"To use a computer package intelligently and safely, you need to have in reserve the ability to do the calculation by hand, at least approximately, so as to appreciate which factors contribute to the risk. Bridge's book is very thorough. Every combination of pedigree structure and marker data is discussed, with numerous tables showing the result of systematically varying one or more parameter." -- Journal of Medical Genetics, reviewing a previous edition or volume
"A useful reference book." -- American Journal of Human Genetics, reviewing a previous edition or volume
Descrizione del libro
The fundamentals of how scientists start with laboratory results and end up with numbers representing genetic risks.
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The Calculation Of Genetic Risks: Worked Examples In Dna Diagnostics
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Johns Hopkins Univ Press, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
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Hardcover. Condizione: Very Good. Condizione sovraccoperta: No Dustjacket. Later Edition. ISBN 9780801857447. Hardback. Second edition. No dustjacket; bound in gray boards with gold gilt lettering on black field. Very slight wear to corners and edges; otherwise tight, sound and unmarked in Very Good to Near Fine condition. No Signature. Codice articolo 4218891
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The Calculation of Genetic Risks: Worked Examples in DNA Diagnostics
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The Johns Hopkins University Pre, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
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The Calculation of Genetic Risks: Worked Examples in DNA Diagnostics
Editore:
The Johns Hopkins University Press, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
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Condizione: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Codice articolo Z1-I-032-02442
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