Sinossi
Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data.
Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics.
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Informazioni sull?autore
Principal Scientist, Analytical Research & Development, Pfizer, Inc., Sandwich, UK
Dalla quarta di copertina
Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data.
Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics.
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Pharmaceutical Applications of Raman Spectroscopy (Wiley Series on Technologies for the Pharmaceutical Industry)
Editore:
Wiley-Interscience, 2007
ISBN 10: 0813810132
ISBN 13: 9780813810133
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Hardcover. Condizione: Good. 1st Edition. Hardcover, xiv + 264pp + 4 pages of glossy colour plates. No title page; faint residue of a removed label inside the front board; mild internal creasing. Book is clean and bright with unmarked text, free of stamps, firmly bound. Boards show shelfwear and scratches, short corner creases. Issued without a dust jacket. -- Contents: 1. Introduction to Raman Spectroscopy (Yukihiro Ozaki and Slobodan Sasic) 1.1 History of Raman Spectroscopy 1.2. The Principle of Raman Spectroscopy 1.3 An Example of Simpel Raman Spectrum: Raman Spectrum of Water 1.4 Characteristics of Raman Spectroscopy 1.5 The Classic Theory of Raman Effect 1.6 The Quantum Theory of Raman Scattering 1.7 Cross Section 1.8 Relevance to Pharmaceuticals 1.9 Resonance Raman Effect 1.10 Instrumentation for Raman Spectroscopy 2. Quantitative Analysis of Solid Dosage Formulations by Raman Spectroscopy (Steven E.J.Bell) 2.1 Introduction 2.2 Quantitative Analysis 2.3 Instrumental Parameters 2.4 Experimental Considerations 2.5 Nonstandard Samples 2.6 Conclusions 3. Surface Enhanced Resonance Raman Scattering (W. Ewen Smith) 3.1 Theory 3.2 The Experimental Setup 3.3 Examples of SERS/SERRS Assays 4. Raman Spectroscopy for Identifying Polymorphs (Fred Laplant and Anne De Paepe) 4.1 Introduction of Polymorphism 4.2 Instrumental Methods of Polymorph Characterization 4.3 Polymorph Screening 4.4 Process Control 4.5 Polymorph Quantitation 4.6 Calibration Set and Sample Preparation 4.7 Quantitation 4.8 Intellectual Property 5. Raman Spectroscopy for Monitoring Real-time Processes in the Pharmaceutical Industry (Kevin L. Davis, Mark S. Kemper and Ian R. Lewis) 5.1 Introduction 5.2 A Brief History of Raman Spectroscopy 5.3 Basic Theory of Raman Spectroscopy 5.4 General Instrumentation for Raman Spectroscopy 5.5 The Choice-Dispersive or FT? 5.6 Process Analysis and PAT 5.7 Why Choose Raman as a PAT Tool? The Need for Raman 5.8 Data Analysis 5.9 Applications 5.10 Conclusions 6. Raman Chemical Imaging of Solid Dosage Formulations (Slobodan Sasic) 6.1 Methods for Chemical Imaging 6.2 Data Analysis 6.3 Experimental 6.4 Applications 7. In vivo Raman Confocal Microspectroscopy of Skin (Andre van der Pol, William M. Riggs and Peter J. Caspers) 7.1 Introduction 7.2 Applications 7.3 Summary and Discussion 8. Raman Microspectroscopy and Imaging of Active Pharmaceutical Ingredients in Cells (Jian Ling) 8.1 Introduction 8.2 Current Approaches to Drug Imaging 8.3 Raman Spectroscopy and Raman Imaging 8.4 Raman Microspectroscopy and Imaging for Drug Research 8.5 Raman Intensity, Fluorescence Background, and SNR 8.6 Techniques to Improve SNR in Raman Imaging 8.7 Enhanced Raman Images with Postprocessing 8.8 Raman Imaging of Intracellular Distribution of Paclitaxel in Living Cells 8.9 Raman Imaging of Intracellular Distribution of Sulindac Sulfide in Fixed Cells 8.10 Conclusions and Future Outlook; Index. Codice articolo 007043
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Pharmaceutical Applications of Raman Spectroscopy (Hardcover)
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ISBN 10: 0813810132
ISBN 13: 9780813810133
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Hardcover. Condizione: new. Hardcover. Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics. Placing an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9780813810133
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Condizione: New. Placing an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Editor(s): Sasic, Slobodan. Series Editor(s): Ekins, Sean. Series: Wiley Series on Technologies for the Pharmaceutical Industry. Num Pages: 264 pages, Illustrations (some col.). BIC Classification: PN. Category: (P) Professional & Vocational. Dimension: 238 x 163 x 18. Weight in Grams: 524. . 2007. 1st Edition. Hardcover. . . . . Codice articolo V9780813810133
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ISBN 13: 9780813810133
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Hardcover. Condizione: new. Hardcover. Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics. Placing an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Codice articolo 9780813810133
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