The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms, test for understanding basic concepts, and pose research-based problems. The Problems Book has been designed to correspond with the first twenty chapters of Molecular Biology of the Cell, Fifth Edition.
The Problems Book will be useful for homework assignments and as a basis for class discussion. It could even provide inspiration for exam questions.
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John Wilson received his PhD from the California Institute of Technology and did his postdoctoral work at Stanford University. He is currently Professor of Biochemistry and Molecular Biology at Baylor College of Medicine, with research interests in genome stability and gene therapy. He has taught medical and graduate students for many years, co authored books on immunology, molecular biology, and biochemistry, and received numerous teaching honors, including the Distinguished Faculty and Robertson Presidential Awards for excellence in education.
Tim Hunt received his PhD in biochemistry from Cambridge University, where he supervised undergraduates in cell biology for more than 20 years. He spent many summers in the late 1970s and early 1980s teaching molecular biology at the Marine Biological Laboratories in Woods Hole, Massachusetts. In 1990, he moved to a position at ICRF Clare Hall Laboratories just outside London, where he works on the control of the cell cycle. He is a Fellow of The Royal Society of London and a foreign associate of the US National Academy of Sciences. In recognition of his contribution to the discovery of key regulators of cell cycle, he was one of the recipients of the 2001 Nobel Prize for Physiology or Medicine.Contenuti:
1. Cells and Genomes
2. Cell Chemistry and Biosynthesis
4. DNA, Chromosomes, and Genomes
5. DNA Replication, Repair and Recombination
6. How Cells Read the Genome: From DNA to Protein
7. Control of Gene Expression
8. Manipulating Proteins, DNA and RNA
9. Visualizing Cells – NEW TO THIS EDITION
10. Membrane Structure
11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes
12. Intracellular Compartments and Protein Sorting
13. Intracellular Vesicular Transport
14. Energy Conversion: Mitochondria and Chloroplasts
15. Mechanisms of Cell Communication
16. The Cytoskeleton
17. The Cell Cycle
19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix – NEW TO THIS EDITION
20. Cancer – NEW TO THIS EDITION
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