Designed to aid toxicology testing study design, this text provides data on issues such as species selection, dose level and dosing regimes, animal models, routes of exposure, statistical evaluation, data interpretation, fulfillment of regulatory requirements, and adherence to good laboratory practices.
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Use of animals in toxicology studies; acute toxicity testing; multidose toxicity and carcinogenicity studies; metabolism and toxicokinetics; inhalation toxicology; genetic toxicology; developmental and reproductive toxicology; neurotoxicity; toxicologic pathology assessment; good laboratory practice compliance; use of transgenic animals for assessment of mutation and cancer; health risk assessment of environmental agents -incorporation of emerging scientific information.
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