Chemokines in Allergic Disease - Rilegato

Rothenberg, Marc E.

Rilegato

ISBN 10: 0824702867 ISBN 13: 9780824702861

Casa editrice: CRC Press, 1999

Riassunto

Supplies more than 2200 references to encourage ongoing research!
This one-of-a-kind volume synthesizes the latest breakthroughs in the fields of allergy and chemokines resulting in innovative paradigms and new concepts concerning the origin and treatment of allergic diseases.
Considers the biological properties of nearly 60 structurally related chemokines and over a dozen receptors!
Fashioned to give an up-to-date overview of molecular structure, gene regulation, biological properties, and signal transduction pathways, Chemokines in Allergic Disease

documents the emergence of chemokines as an important super family of chemoattractant cytokines that promote the activation and development of leukocytes

illuminates the processes that control leukocyte accumulation

links chemokines with cell recruitment and activation in allergic disease

explores the benefits of pharmaceutical intervention in the chemokine pathway

covers the fundamental biochemistry, molecular biology, and physical structure of chemokines and their receptors

describes transcriptional regulation of chemokine expression

discusses virally induced gene expression as a main trigger of allergic responses in children

analyzes eosinophils, basophils, T lymphocytes, dendritic cells, and macrophages

elucidates the cellular network involved in the generation of chemokines in allergic diseases

highlights pharmaceutical approaches for the development of chemokine structural analogs, receptor antagonists, and inhibitors of signal transduction

offers therapeutic strategies for interfering with chemokines in allergic disorders

and more!
With contributions from 46 internationally respected clinicians, Chemokines in Allergic Disease is an indispensable reference for basic and clinical immunologists; allergists; pulmonologists and pulmonary disease specialists; physiologists; molecular, cellular, and lung biologists; pediatricians; internists; and graduate and medical school students in these disciplines.

Su questo libro

Contenuti

Basic Science of Chemokines and Their Receptors

Overview,
Marc E. Rothenberg and Simon P. Hogan
The Chemokine Family,
Joost J. Oppenheim, O. M. Zack Howard, and Joseph A. Hedrick
Chemokine Receptors,
Philip M. Murphy and Marc E. Rothenberg
Three-Dimensional Structure of Chemokines,
Martin J. Stone and Kristen R. Mayer

Basic Science of Chemokines and Allergic Disease

Animal Allergy Models: Dissecting Chemokine Function,
D. M. Conroy and Timothy Williams
Transcriptional Regulation of Chemokines,
Ya-Fen Chen, An Song, and Alan M. Krensky
Chemokines and Histamine-Releasing Factors,
Allen P. Kaplan
Eosinophil Chemokines,
Marc E. Rothenberg and Nives Zimmermann
Basophil Chemokines,
Clemens A. Dahinden
Dendritic Cells, T Lymphocytes, and Chemokines,
David R. Greaves and Thomas J. Schall
Differential Production and Function of Chemokines During Th1/Th2 Type Responses,
Emma M. Campbell, Steven L. Kunkel, and Nicholas W. Lukacs
Chemokines for Immature Blood Cells: Effects on Migration, Proliferation, and Differentiation,
Chang H. Kim and Hal E. Broxmeyer
The Induction of Chemokines by Viruses in Allergic States,
James M. Stark
Chemokine and Cytokine Cooperativity,
Ljubov Simson and Paul Stephen Foster
Chemokine Receptor Signal Transduction Mechanisms,
Ann Richmond, Wei Yang, and Madhav N. Devalaraja

Clinical Science of Chemokines in Allergic Disease

Chemokines and Disease,
Andrew D. Luster, Sylvie Abi-Younes, and Andrew M. Tager
Chemokines in Allergic Asthma,
Sun Ying and A. B. Kay
Cellular Sources of Chemokines in Allergic Diseases,
Omar Ghaffar, Pota Christodoulopoulos, and Qutayba Hamid
Chemokines in Allergic Rhinitis,
Rafeul Alam
Chemokines in Ocular Allergy and Inflammation,
Eric Pearlman
Chemokines in Allergic Cutaneous Disorders,
Jens-Michael Schröder

Pharmaceutic Strategies for Allergies

Regulation of Chemokines by Glucocorticoids,
Cristiana Stellato and Robert P. Schleimer
Chemokine Analogues,
Amanda E. I. Proudfoot, Christine A. Power, and Timothy Wells
Chemokine Receptor Blockade,
Paul D. Ponath

Product Description

Book by Rothenberg Marc E

Dettagli dell'edizione

• Editore: CRC Press
• Data di pubblicazione: 1999
• Lingua: Inglese
• ISBN 10: 0824702867
• ISBN 13: 9780824702861
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 592
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile