Chromosomal Instability and Aging: Basic Science and Clinical Implications - Rilegato

Hisama, Fuki; Weissman, Sherman M.; Martin, George M.

Rilegato

ISBN 10: 0824708563 ISBN 13: 9780824708566

Casa editrice: CRC Press, 2003

Riassunto

This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability, and aging. The authors provide in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage to assess their impact on the modulation of aging processes and age-related diseases, including cancer development. Chromosomal Instability and Aging describes cloning genes for human chromosomal instability disorders, the causal factors and consequences of chromosomal injury, the telomere hypothesis of aging, and age-dependant mitochondrial genetic instability. It includes more than 2200 references to facilitate further research, making it an informative and timely guide.

Su questo libro

Informazioni sull'autore

Fuki Hisama, Sherman M. Weissman, George M. Martin

Dettagli dell'edizione

• Editore: CRC Press
• Data di pubblicazione: 2003
• Lingua: Inglese
• ISBN 10: 0824708563
• ISBN 13: 9780824708566
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 608
• Contatto del produttore: Taylor and Francis, GPSR Taylor and Francis; gpsr@taylorandfrancis.com; ; Taylor & Francis Verlag GmbH, Kaufingerstraße 24; München; 80331; Germania