This resource discusses the principles and techniques of diode array detectors, compares them to conventional absorbance detectors, and examines their applications in high-performance liquid chromatography.;Providing guidelines on how to optimize diode array detectors for high sensitivity, selectivity, linearity and automation, Diode Array Detection in HPLC presents: early developments in diode array technology; current areas of application; computer techniques for spectral library searching; the mathematical basis of spectral deconvolution; practical uses of ultraviolet spectra for peak purity control and peak confirmation; chromatographic examples for HPLC applications, and more.;Diode Array Detection in HPLC is a practical guide for analytical, food, and pharmaceutical chemists and biochemists; analytical laboratory managers, consultants, and operators; and upper-level undergraduate, graduate, and continuing-education students in these disciplines.
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Historical developments, Stephan A. George; modern developments, Stephan A. George; diode array detection advantages for the chromatographer, Stephan A. George; spectral matching and peak purity, Hans-Jurgen P. Sievert and Anton C.J.H. Drouen; chemometrics and photodiode array detection, Joost K. Strasters; the use of diode array detectors in the pharmaceutical industry, Robert Giuffre; clinical applications, Ludwig Huber; applications in the analysis of amino acids, peptides and proteins, Gerard P. Rozing; food and beverages, Ludwig Huber and Rainer Schuster; environmental applications, Ludwig Huber and Rainer Schuster; chemical, petrochemical and polymer applications, Ludwig Huber; optimization of diode array detection for sensitivity, selectivity, wavelength resolution, and linearity, Ludwig Huber; using diode array detectors for automated routine analysis, Ludwig Huber.
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