Highlighting the transition from basic research to clinical applications, this unique reference presents the endothelium as both the source and the target of novel therapeutic concepts and discusses the involvement of the endothelium in mainstream approaches to the treatment of various conditions.
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The Endothelium as the Source of Novel Therapies
Prostacyclin (Prostaglandin I2) and Atherosclerosis, Karsten Schrör
Prostacyclin and Thromboxane: Role in Ischemic Heart Disease, Jawahar L. Mehta and Baichun C. Yang
Clinical Use of Prostacyclins, John A. Dormandy and Glyn Belcher
Nitric Oxide Synthases: Enzymology and Mechanism-Based Inhibitors, John F. Parkinson and Gary Phillips
Endothelin: From Basic to Pathophysiological Research, Katsutoshi Goto
Transmigration of Leukocytes, B. Stein, Y. Khew-Goodall, J. Gamble, and M. A. Vadas
Transforming Growth Factor-b and Cardiovascular Protection, David J. Grainger and James C. Metcalfe
Coagulation Factors, Michael Kalafatis, Jack O. Egan, and Kenneth G. Mann
The Endothelium as a Target for Novel Therapies
Endothelial Dysfunction and Vascular Disease, Paul M. Vanhoutte, Louis Perrault, and Jean Paul Vilaine
Complement and Endothelium: Novel Complement-Inhibitory Therapeutics, Una S. Ryan
The Receptor for Advanced Gycation Endproducts: Implications for the, Development of Diabetic Vascular Disease, Osamu Hori, Shi Du Yan, and Ann Marie Schmidt
Hypertension, Pierre Moreau and Thomas F. Lüscher
Arterial Restenosis, Michael A. Reidy and Stephen M. Schwartz
Pathobiology and Clinical Consequences of Plaque Rupture, Richard Gallo, Juan J. Badimon, James H. Chesebro, Valentin Fuster, and Lina Badimon
Isoprostanes and Antioxidant Therapy in Human Diseases, Emma A. Meagher and Garrett A. FitzGerald
Vasculoprotection by Estrogen Contributes to Gender Difference in Cardiovascular Diseases: Potential Mechanism and Role of Endothelium, Katalin Kauser and Gabor M. Rubanyi
Lipoprotein(a): Insights from Transgenic Mice, Steven D. Hughes and Edward M. Rubin
Gene Therapy
Gene Therapy with Vascular Endothelial Growth Factor, Jeffrey M. Isner
Vascular Disease and the Prospect of Gene Therapy, Heiko E. von der Leyen and Victor J. Dzau
Book by Rubanyi Gabor
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