Structure-Based Drug Design - Rilegato

Rilegato

ISBN 10: 0824798694 ISBN 13: 9780824798697

Casa editrice: Routledge, 1997

Riassunto

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

Su questo libro

Informazioni sull?autore

Pandi Veerapandian

Dettagli dell'edizione

• Editore: Routledge
• Data di pubblicazione: 1997
• Lingua: Inglese
• ISBN 10: 0824798694
• ISBN 13: 9780824798697
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 664
• Redattore: Veerapandian Pandi
• Contatto del produttore: Taylor and Francis, GPSR Taylor and Francis; gpsr@taylorandfrancis.com; ; Taylor & Francis Verlag GmbH, Kaufingerstraße 24; München; 80331; Germania