A Practical Guide to Combinatorial Chemistry - Rilegato

Rilegato

ISBN 10: 084123485X ISBN 13: 9780841234857

Casa editrice: American Chemical Society, 1999

Riassunto

This book is a practical guide for those engaged in small-molecule combinatorial chemistry as well as those wishing to learn the field. Aimed at nonspecialists, the chapters are written in a tutorial style by internationally recognized experts. The text reviews the use of computational tools to analyse molecular diversity and presents a detailed survey of solid-phase peptide synthesis and the tools used for small-molecule synthesis. Up-to-date automated approaches and equipment for synthesizing solid- and solution-phase libraries are reviewed, including synthesis, analytical, and deconvolution tools. This book will be useful to medicinal chemists, organic chemists, biochemists engaged in high-throughput screening, materials scientists, patent professionals, and science writers.

Su questo libro

Contenuti

• 1: Walter H. Moos: Introduction: Combinatorial Chemistry Approaches the Next Millenium
• 2: Peter Willett: Using Computational Tools to Analyze Molecular Diversity
• Solid-Phase Strategies
• 3: George Barany and Maria Kempe: Solid Phase Synthesis: Context
• 4: John S Kiely, Thomas K Hayes, Michael C. Griffith, and Yazhong Pei: Synthesis Tools for Solid-Phase Synthesis
• 5: Michael J. Shapiro, Mengfen Lin, and Bing Yan: On-Resin Analysis in Combinatorial Chemistry
• 6: John J. Baldwin and Roland Dolle: Deconvolution Tools for Solid-Phase Synthesis
• Solution-Phase Strategies
• 7: Ted L. Underiner and John R. Peterson: Synthesis Tools for Solution-Phase Synthesis
• 8: Christopher E. Kibbey: Analytical Tools for Solution-Phase Synthesis
• 9: Xavier Willard and André Tartar: Deconvolution Tools in Solution-Phase Synthesis
• Equipment and Automation
• 10: Ralph A. Rivero, Michael N. Greco, and Bruce Maryanoff: Equipment for the High Throughput Organic Synthesis of Chemical Libraries
• 11: Jonathan S. Lindsey: Automated Approaches to Reaction Optimization
• 12: Adnan M. M. Mjalli: Application of Automated Parallel Synthesis
• Information Management and Biological Applications
• 13: Steven M. Muskal: Information Management
• 14: F. F. Craig: Screening of Combinatorial Libraries
• 15: Anthony W. Czarnik and Sheila Hobbs Dewitt: Summary

Product Description

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Dettagli dell'edizione

• Editore: American Chemical Society
• Data di pubblicazione: 1999
• Lingua: Inglese
• ISBN 10: 084123485X
• ISBN 13: 9780841234857
• Rilegatura: Copertina rigida
• Numero di pagine: 360
• Redattore: Czarnik Anthony W., DeWitt Sheila Hobbs
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile