Toxicology: Principles and Applications - Rilegato

Niesink, Raymond; Hollinger, Mannfred A.; De Vries, John

Rilegato

ISBN 10: 0849392322 ISBN 13: 9780849392320

Casa editrice: CRC Press, 1996

Riassunto

Focusing primarily on basic principles and concepts, Toxicology also provides 200 tables worth of toxicological data. Each heavily illustrated chapter is a complete study unit containing a table of contents, an introduction, a learning core, a self-test, and feedback. The main text for the unit is followed by a self-test, which reveals whether the learning objectives have been met. The feedback section answers frequently asked questions, while a summary enables the student to review the main concepts before moving on to the next unit.

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Contenuti

FUNDAMENTAL PRINCIPLES
Toxicology: History and Scope of the Field, J.H. Koeman
Exposure: Qualitative and Quantitative Aspects, A. Musch
Biotransformation: Detoxification and Bioactivation, B.J. Blaauboer
Biotransformation: Species Differences and Determining Factors, A. Bast
Absorption, Distribution, and Elimination of Xenobiotics, R.J.M. Niesink
Toxicokinetics: Quantitative Aspects, J. de Vries
Dose-time-effect Relationships, A. Musch

MOLECULAR ASPECTS OF TOXICITY
Structure-activity Relationships, J.L.M. Hermens
Toxicity of Mixtures, A. Musch
Cytotoxicity: Molecular Mechanisms of Cell Death, J. de Vries
Genetic Toxicology, Ph. Vanparys and F.-J. van Schooten
Introduction to Carcinogenesis, H. van Cauteren, Th.M.C.M. de Kok, and F.-J. van Schooten
Cancer Risk Evaluation, H. van Cauteren, Th.M.C.M. de Kok, and F.-J. van Schooten

ORGAN TOXICOLOGY
Toxicity Testing, Risk Assessment, Regulation, and Legislation, K.N. Woodward
Cytopathology: General Response Patterns and Morphological Aspects, A. Penninks
Necrosis and Apoptosis: Irreversibility of Cell Damage and Cell Death, A. Verheyen

ORGANS INVOLVED IN ABSORPTION AND ELIMINATION
Dermatotoxicology: Toxicological Pathology and Methodological Aspects, R.J.M. Niesink
Respiratory Toxicology: Pathophysiology, Toxicological Pathology, and Mechanisms of Toxicity, R.B. Beems, V.J. Feron, P.G.J. Reuzel, and A. Zwart
Inhalatory Exposure and Methodological Aspects, R.B. Beems, V.J. Feron, P.G.J. Reuzel, and A. Zwart
Gastro-intestinal Toxicology: Structure, Function, and Intestinal Toxicity, W. Coussement
Gastro-intestinal Toxicology: Toxicological Pathology and Sources of Intestinal Toxicity, W. Coussement
Hepatotoxicology: Structure, Function, and Toxicological Pathology, J. Vandenberghe
Hepatotoxicology: Mechanisms of Liver Toxicity and Methodological Aspects, J. Vandenberghe
Nephrotoxicology: Toxicological Pathology and Biochemical Toxicology, J.F. Nagelkerke
Organ Perfusion Techniques: In Vitro Toxicity Testing, A. Sj. Koster

ORGANS INVOLVED IN MAINTAINING HOMEOSTASIS
Cardiovascular Toxicology: Toxicological Pathology and Methodological Aspects, A. Verheyen
Toxicology of the Blood: Pathophysiology, Toxicological Pathology, and Mechanistic Aspects, J.J. Marx
Immunotoxicology: Determination of Immunotoxic Effects and Immunotoxicity Mechanisms, H. van Loveren and J.G. Vos
Immunotoxicology: Examples of Immunotoxic Substances, H. van Loveren and J.G. Vos
Endocrinotoxicology: Methodological Aspects, M.A.M. Krajns-Franken, F.X.R. van Leeuwen, and J.G. Loeber
General Reproductive Toxicology, J.M. Garbis-Berkvens, P.W.J. Peters
Special Reproductive Toxicology, J.M. Garbis-Berkvens and P.W.J. Peters
Anatomy and Toxicological Pathology of the Nervous System, A. Bast
Functional Neurotoxicology, T.A. de Vlieger
Neurobehavioral Toxicology, R.J.M. Niesink

APPLICATION AREAS
Introduction to Nutritional Toxicology, J.H. Koeman
Food Toxicity: The Toxicological History of Aspartame, J.C.S. Kleinjans
Medical and Clinical Toxicology, B. Sangster
Ecotoxicology, N.M. van Straalen
Occupational Toxicology, P.J.A. Borm and P.Th. Henderson
Achievement Test
Abbreviations
Formula Index
Glossary of Terms
Literature
Index

Product Description

Book by Niesink Raymond Hollinger Mannfred A De Vries John

Dettagli dell?edizione

• Editore: CRC Press
• Data di pubblicazione: 1996
• Lingua: Inglese
• ISBN 10: 0849392322
• ISBN 13: 9780849392320
• Rilegatura: Copertina rigida
• Numero edizione: 1
• Numero di pagine: 1312
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile