The Development of a New Triphasic Oral Contraceptive: The Proceedings of a Special Symposium Held at the 10th World Congress on Fertility and Sterility, Madrid July 1980 - Rilegato
Contenuti
1 A Retrospective View of Oral Contraceptives.- 2 The Rationale for a New Triphasic Contraceptive.- 3 The Normal Menstrual Cycle and Oral Contraceptives: The Physiological Basis for a Triphasic Approach.- 4 Mode of Action of Triphasic Oral Contraception.- 5 Effects of Some Ethinyloestradiol/Levonorgestrel Combinations on SHBG and on Lipid Metabolism.- 6 A Randomized Study of Metabolic Effects of Four Oral Contraceptive Preparations Containing Levonorgestrel plus Ethinyloestradiol in Different Regimens.- 7 Clinical Investigations with a New Triphasic Oral Contraceptive.- 8 Canadian Experience with Two Triphasic Oral Contraceptive Formulations.- Discussion.- Summary.
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The Development of a New Triphasic Oral Contraceptive: The Proceedings of a Special Symposium held at the 10th World Congress on Fertility and Sterility, Madrid July 1980
Da: Bookbot, Prague, Repubblica Ceca
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Hardcover. Condizione: Fair. Unbekannte Unterschrift / Widmung / Aufkleber; Anmerkungen / bekritzelt / Stempel; Abnutzung / Risse - leicht. R. B. GREENBLATT discusses the evolution of oral contraceptives, highlighting that early formulations contained higher doses of oestrogen (ethinyloestradiol or mestranol) and progestagen (norethynodrel or norethisterone) than necessary for effective conception control. Over time, there has been a trend towards reducing these dosages to minimize side effects while maintaining efficacy. However, lower dosages have led to increased instances of spotting and breakthrough bleeding in the initial months of use. The sequential pill, which aimed to align more closely with physiological principles, required larger doses of oestrogen to prevent ovulation, resulting in a higher pregnancy rate and making it less appealing. A new triphasic formulation has emerged that leverages the synergy between ethinyloestradiol and levonorgestrel, allowing for low doses of oestrogen and very low doses of progestagen to be used effectively. This preparation is associated with fewer side effects, adhering to the pharmacological principle of minimal dosing for desired outcomes. The regimen divides the cycle into three phases, using varying doses of oestrogen over 21 days, closely mimicking the natural hormonal fluctuations in the menstrual cycle. Codice articolo b5a42608-4b60-4bb6-bdcb-f1bcbe71e9d5
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The Development of a New Triphasic Oral Contraceptive
Editore:
MTP Press - International Medical Publishers, Lancaster, UK, 1980
ISBN 10: 0852003765
ISBN 13: 9780852003763
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Rilegato
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Da: Klanhorn, Queanbeyan, NSW, Australia
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Hard Cover with Dust Jacket. Condizione: Very Good ++. Condizione sovraccoperta: Very Good. 1st Edition. VG++, Shelfwear/VG, Edgewear, small tears, indentations. The Proceedings of a Special Symposium held at the Xth World Congress on Fertility and Sterility, Madrid July 1980. 128 pages. Illustrated with graphs. Expanded condition report/scan on request. Codice articolo 019915
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The Development of a New Triphasic Oral Contraceptive. The Proceedings of a Special Symposium held at the 10th World Congress on Fertility and Sterility, Madrid, July 1980
Editore:
MTP Press Limited, Falcon House, Lancaster, England, 1980
ISBN 10: 0852003765
ISBN 13: 9780852003763
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Rilegato
Prima edizione
Da: Book Souk, Porstoy, Regno Unito
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Hardcover. Condizione: Very Good. 1st Edition. 252 grams. Codice articolo 006380
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