Internationally known scientists review what has been accomplished thus far in developing acceptable alternatives to classical animal toxicity assessment methods. Authoritative chapters describe not only the many practical alternative approaches that have recently emerged, but also consider current trends and likely future approaches, as well as emerging automated assessment techniques. Hazard assessment applications and the validation of new alternative methods are also discussed. The methods presented here will help toxicologists, cosmetic chemists, and pharmacologists greatly reduce, refine, or even possibly replace, the use of laboratory animals in their work. Life science researchers will also find many new opportunities for detecting endocrine disruptions. Regulatory officers will gain a new perspective on alternative assessment, environmental assessment, and risk assessment. Significantly extending the efforts of the National Institutes of Health, the European Union, and the ICCVAM, Toxicity Assessment Alternatives offers all those evaluating toxicity today a cutting-edge collection of practical and highly effective alternatives.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
In Toxicity Assessment Alternatives, internationally known scientists review what has been accomplished thus far in developing acceptable alternatives to classical animal toxicity assessment methods. Authoritative chapters describe not only the many practical alternative approaches that have recently emerged, but also consider current trends and likely future approaches, as well as emerging automated assessment techniques. Hazard assessment applications and the validation of new alternative methods are also discussed. The methods described here will help toxicologists, cosmetic chemists, and pharmacologists greatly reduce, refine, or even possibly replace, the use of laboratory animals in their work. Life science researchers will also find many new opportunities for detecting endocrine disruptions. Regulatory officers will gain a new perspective on alternative assessment, environmental assessment, and risk assessment.
Significantly extending the efforts the National Institutes of Health, the European Union, and the ICCVAM, Toxicity Assessment Alternatives offers all those evaluating toxicity today a cutting-edge collection of practical and highly effective alternative methods.
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Da: Zubal-Books, Since 1961, Cleveland, OH, U.S.A.
Condizione: Good. 262 pp., Hardcover, ex library, else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country. Codice articolo ZB870097
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Da: The Book Exchange, Macclesfield, CHESH, Regno Unito
Hardcover. Condizione: Near Fine. 0896037878. Pictorial board hardcover, from closed pharmaceutical company library. Lending record shows this book has never been borrowed. 262 pages, index, illustrated with charts, tables and diagrams. Describe alternative approaches as well as automated assessment techniques. Hazard assessment applications and the validation of alternative methods are also discussed. The methods presented here will help toxicologists, cosmetic chemists, and pharmacologists reduce, refine, or even replace, the use of laboratory animals in their work. Contents clean, tight and bright. Book. Codice articolo 027207
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Da: SHIMEDIA, Brooklyn, NY, U.S.A.
Condizione: New. Satisfaction Guaranteed or your money back. Codice articolo 0896037878
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Da: BennettBooksLtd, Los Angeles, CA, U.S.A.
Hardcover. Condizione: New. In shrink wrap. Looks like an interesting title! Codice articolo Q-0896037878
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Da: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. Codice articolo ABBB-166535
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Da: Basi6 International, Irving, TX, U.S.A.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. Codice articolo ABEOCT25-133395
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Da: Books Puddle, New York, NY, U.S.A.
Condizione: Used. pp. 280. Codice articolo 26289444
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Da: Majestic Books, Hounslow, Regno Unito
Condizione: Used. pp. 280 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam. Codice articolo 7591291
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Da: Biblios, Frankfurt am main, HESSE, Germania
Condizione: Used. pp. 280. Codice articolo 18289454
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Toxicity Assessment Alternatives: Methods, Issues, Opportunities contains a broad array of critical surveys, contributed by active and respected investigators, describing their research and offering updates on toxicity assessment alternatives, directions determined by current and future grant programs, opportunities for mechanistically based test methods to detect endocrine disruptor activity, the use of alternatives in the Department of Defense hazard assessment initiatives, and the issues and opportunities for validation and regulatory acceptance. Several of these advances make use oftransgenic models that reduce the time and cost of carcinogenicity testing. Others use tissue cultures for the assessment of endocrine disrupting chemicals. Cultures of human epidermal keratinocytes are applicable as models for sulfur mustard lesions, and in vitro protein denaturation is used as a chemical test for assessing the ocular and dermal irritation potential of cosmetic prod ucts. Molecular modeling is applied to explaining chemical toxicity. Commercially developed assay systems have undergone extensive evaluation by their manufacturers. Some of these await external valida tion, and others await acceptance by North American and European regulatory agencies. Toxicity Assessment Alternatives: Methods, Issues, Opportunities provides information from members of the scientific and regulatory communities on what has been achieved and what has been accepted in alternatives to animal testing. 288 pp. Englisch. Codice articolo 9780896037878
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