Posttranslational Modification Of Proteins: Expanding Nature's Inventory - Rilegato

Walsh, Christopher T.

Rilegato

ISBN 10: 0974707732 ISBN 13: 9780974707730

Casa editrice: W H Freeman & Co, 2005

Riassunto

Covering the major classes of posttranslational modifications, Posttranslational Modification of Proteins is the first comprehensive treatment of this burgeoning area of proteome diversification.

Su questo libro

Informazioni sugli autori

Professor Walsh is currently the Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He is one of the leading enzymologists in the world. He has elucidated the catalytic mechanisms of a wide variety of enzymes including flavoproteins and other redox enzymes. He has also pioneered the design of mechanism-based enzyme inhibitors (or "suicide" substrates). His work has found practical application in the design of antibacterial agents, anticonvulsive agents, plant growth regulators, and antitumor drugs. His current focus is on the biosynthesis and mechanism of action of antibiotics and bacterial siderophores. He has published over 600 scientific articles and his book, Enzymatic Reaction Mechanisms, has educated generations of enzymologists.

Professor Walsh's accomplishments have been recognized through numerous awards which include the Eli Lilly Award in Biochemistry, the Arthur C. Cope Scholar Award in Organic Chemistry, the Repligen Award in Biological Chemistry, and the Alfred Bader Award in Bioorganic and Bioinorganic Chemistry. He is a member of the National Academy of Sciences, the Institute of Medicine, and the American Academy of Arts and Sciences.

Professor Walsh is currently the Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He is one of the leading enzymologists in the world. He has elucidated the catalytic mechanisms of a wide variety of enzymes including flavoproteins and other redox enzymes. He has also pioneered the design of mechanism-based enzyme inhibitors (or "suicide" substrates). His work has found practical application in the design of antibacterial agents, anticonvulsive agents, plant growth regulators, and antitumor drugs. His current focus is on the biosynthesis and mechanism of action of antibiotics and bacterial siderophores. He has published over 600 scientific articles and his book, Enzymatic Reaction Mechanisms, has educated generations of enzymologists.

Dalla quarta di copertina

More than five percent of the genes in higher eukaryotic genomes encode enzymes that posttranslationally modify proteins, greatly expanding the complexity and diversity of proteomes. This book examines the molecular logic of the major types of covalent modifications of proteins and their biological consequences.

Dettagli dell?edizione

• Editore: W H Freeman & Co
• Data di pubblicazione: 2005
• ISBN 10: 0974707732
• ISBN 13: 9780974707730
• Rilegatura: Copertina rigida
• Lingua: Inglese
• Numero di pagine: 490
• Contatto del produttore: non disponibile