Computational Toxicology: Risk Assessment for Chemicals - Rilegato

 
9781119282563: Computational Toxicology: Risk Assessment for Chemicals
Rilegato
ISBN 10: 111928256X ISBN 13: 9781119282563
Casa editrice: John Wiley & Sons Inc, 2018

Sinossi


A key resource for toxicologists across a broad spectrum of fields, this book offers a comprehensive analysis of molecular modelling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals.

•    Provides a perspective of what is currently achievable with computational toxicology and a view to future developments
•    Helps readers overcome questions of data sources, curation, treatment, and how to model / interpret critical endpoints that support 21st century hazard assessment
•    Assembles cutting-edge concepts and leading authors into a unique and powerful single-source reference
•    Includes in-depth looks at QSAR models, physicochemical drug properties, structure-based drug targeting, chemical mixture assessments, and environmental modeling
•    Features coverage about consumer product safety assessment and chemical defense along with chapters on open source toxicology and big data

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Informazioni sull?autore

Sean Ekins, MSc, PhD, DSc has over 20 years of pharmaceutical and toxicology experience. He is the founder or co-founder of two companies and Adjunct Professor at three universities. He has been awarded 16 NIH grants as Principal Investigator. He has authored or co authored over 285 peer-reviewed papers and book chapters and edited five books with Wiley. His research is focused on collaborations to facilitate rare and neglected disease drug discovery.

Dalla quarta di copertina

Computational Toxicology: Risk Assessment for Chemicals offers a comprehensive analysis of applied approaches and strategies. The book begins with an introduction to toxicology and relevant technologies and then addresses the most advanced currently available molecular-modelling software and its role in toxicity testing.

The chapters feature in-depth looks at QSAR models, physicochemical drug properties, structure-based drug targeting, chemical mixture assessments, and environmental modelling. Additional coverage includes consumer product safety assessment and chemical defense, along with chapters on open source toxicology and big data.

An important resource for researchers and regulators involved in toxicology and risk assessment:

  • Provides a perspective of what is currently achievable with computational toxicology and a view to future developments
  • Helps readers overcome questions of data sources, curation, treatment, and how to model / interpret critical endpoints that support 21st century hazard assessment
  • Assembles cutting-edge concepts and leading authors into a unique and powerful single-source reference

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
John Wiley & Sons Inc
Data di pubblicazione
2018
Lingua
Inglese
ISBN 10 
111928256X
ISBN 13 
9781119282563
Rilegatura
Copertina rigida
Numero di pagine
408
Redattore
Ekins Sean
Contatto del produttore
non disponibile
Persona responsabile
non disponibile