Articoli correlati a Autoimmunity
Sinossi
The immune system has evolved mechanisms enabli ng it to discriminate between self and non-self constituents. A normally functioning organism is naturally unresponsive to self antigens originating from clonal deletion, aner gy, or an active suppression of self-reactive T cells. The wide spectrum of autoimmune responses may be divided into systemic and organ-specific dis eases and encompasses the actions of autoantibodies, autoantigeu-autoanti body complexes, and sensitized T lymphocytes. The aim of this book is to review the current understandin g, concepts and hypotheses regarding the pathogenesis and therapeutic approaches in autoim mune disorders. The first six articles are generally concerned with the mech anisms operating in autoimmune phenomena, whereas the subsequent reviews discuss particular phenomena in representative autoimmune dis eases. The introductory article underlines the significance of the interactions between antigen-specific T cells and other elements ot the immune system and proposes that not suppression, but rather activation of the immune sys tem, leading to a redirection of the immune response, would be therapeuti cally beneficial. The next articles present the importance of costim ulatory signals in determining various types of immune responses, including autoim munity, and the role of regulatory T cells. Further, an interesting phenome non of epitope spreading as a mechanism for the progression of autoimmune diseases is presented.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
The Paradigms of Causality and Treatment for Autoimmune Disease; I.R. Cohen. Uncovering the Differences between T Cell Tolerance and Immunity; A.T. Vella. The Physiological Role of Regulatory T Cells in the Prevention of Autoimmunity: Generation, Specificity and Mode of Action; B. Seddon. Epitope Spreading: a Mechanism for Progression of Autoimmune Disease; V.K. Tuohy, R.P. Kinkel. A Role for NF-kappaB and the Proteasome in Autoimmunity; T. Hayashi, D. Faustman. Complement Regulatory Proteins and Autoimmunity; M. Kawano. Pathogenic Immunity in Theiler's Virus-Induced Demyelinating Disease: a Viral Model for Multiple Sclerosis; B.S. Kim, et al. Evidence that Fas and FasL Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis; B.N. Dittel. The Role of Cytokines in Experimental Autoimmune Encephalomyelitis; E. Bettelli, L.B. Nicholson. Involvement of Apoptotic Protease Cascade for Tissue Destruction in Sjögren's Syndrome; Y. Hayashi. Is Lack of Peripheral Tolerance Induction a Cause for Diabetes in the Non-Obese Diabetic Mouse? T. Lund, J. Strid. Neuro-Endocrine-Immune Axis in Human Rheumatoid Arthritis; T. Sakane, N. Suzuki. The Role of T Cells in Rheumatoid Arthritis; C.M. Weyand, et al. Index.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Autoimmunity
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Condizione: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,600grams, ISBN:9781402000379. Codice articolo 9432571
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Autoimmunity
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Springer Netherlands Sep 2001, 2001
ISBN 10: 1402000375
ISBN 13: 9781402000379
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The immune system has evolved mechanisms enabli ng it to discriminate between self and non-self constituents. A normally functioning organism is naturally unresponsive to self antigens originating from clonal deletion, aner gy, or an active suppression of self-reactive T cells. The wide spectrum of autoimmune responses may be divided into systemic and organ-specific dis eases and encompasses the actions of autoantibodies, autoantigeu-autoanti body complexes, and sensitized T lymphocytes. The aim of this book is to review the current understandin g, concepts and hypotheses regarding the pathogenesis and therapeutic approaches in autoim mune disorders. The first six articles are generally concerned with the mech anisms operating in autoimmune phenomena, whereas the subsequent reviews discuss particular phenomena in representative autoimmune dis eases. The introductory article underlines the significance of the interactions between antigen-specific T cells and other elements ot the immune system and proposes that not suppression, but rather activation of the immune sys tem, leading to a redirection of the immune response, would be therapeuti cally beneficial. The next articles present the importance of costim ulatory signals in determining various types of immune responses, including autoim munity, and the role of regulatory T cells. Further, an interesting phenome non of epitope spreading as a mechanism for the progression of autoimmune diseases is presented. 220 pp. Englisch. Codice articolo 9781402000379
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Autoimmunity
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Condizione: New. In. Codice articolo ria9781402000379_new
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Autoimmunity
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The Paradigms of Causality and Treatment for Autoimmune Disease I.R. Cohen. Uncovering the Differences between T Cell Tolerance and Immunity A.T. Vella. The Physiological Role of Regulatory T Cells in the Prevention of Autoimmunity: Generation, Specif. Codice articolo 4091523
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Autoimmunity
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Condizione: New. Presents a review of the mechanisms underlying the phenomena of autoimmunity. This book presents concepts in the fundamentals and treatment of autoimmune disorders. It opposes the dogma that autoimmune disorders should be treated with immunosuppressors, and postulates rather the activation of the immune system. Editor(s): Gorski, Andrzej; Krotkiewski, Hubert; Zimecki, Michal. Num Pages: 207 pages, biography. BIC Classification: MJ. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 15. Weight in Grams: 537. . 2001. Hardback. . . . . Codice articolo V9781402000379
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Autoimmunity
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Buch. Condizione: Neu. Autoimmunity | Andrzej Górski (u. a.) | Buch | vii | Englisch | 2001 | Springer Netherland | EAN 9781402000379 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 102548058
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Autoimmunity
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Springer Netherlands, Springer Netherlands Sep 2001, 2001
ISBN 10: 1402000375
ISBN 13: 9781402000379
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The immune system has evolved mechanisms enabli ng it to discriminate between self and non-self constituents. A normally functioning organism is naturally unresponsive to self antigens originating from clonal deletion, aner gy, or an active suppression of self-reactive T cells. The wide spectrum of autoimmune responses may be divided into systemic and organ-specific dis eases and encompasses the actions of autoantibodies, autoantigeu-autoanti body complexes, and sensitized T lymphocytes. The aim of this book is to review the current understandin g, concepts and hypotheses regarding the pathogenesis and therapeutic approaches in autoim mune disorders. The first six articles are generally concerned with the mech anisms operating in autoimmune phenomena, whereas the subsequent reviews discuss particular phenomena in representative autoimmune dis eases. The introductory article underlines the significance of the interactions between antigen-specific T cells and other elements ot the immune system and proposes that not suppression, but rather activation of the immune sys tem, leading to a redirection of the immune response, would be therapeuti cally beneficial. The next articles present the importance of costim ulatory signals in determining various types of immune responses, including autoim munity, and the role of regulatory T cells. Further, an interesting phenome non of epitope spreading as a mechanism for the progression of autoimmune diseases is presented.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch. Codice articolo 9781402000379
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Autoimmunity
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Springer Netherlands, Springer Netherlands, 2001
ISBN 10: 1402000375
ISBN 13: 9781402000379
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Da: AHA-BUCH GmbH, Einbeck, Germania
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The immune system has evolved mechanisms enabli ng it to discriminate between self and non-self constituents. A normally functioning organism is naturally unresponsive to self antigens originating from clonal deletion, aner gy, or an active suppression of self-reactive T cells. The wide spectrum of autoimmune responses may be divided into systemic and organ-specific dis eases and encompasses the actions of autoantibodies, autoantigeu-autoanti body complexes, and sensitized T lymphocytes. The aim of this book is to review the current understandin g, concepts and hypotheses regarding the pathogenesis and therapeutic approaches in autoim mune disorders. The first six articles are generally concerned with the mech anisms operating in autoimmune phenomena, whereas the subsequent reviews discuss particular phenomena in representative autoimmune dis eases. The introductory article underlines the significance of the interactions between antigen-specific T cells and other elements ot the immune system and proposes that not suppression, but rather activation of the immune sys tem, leading to a redirection of the immune response, would be therapeuti cally beneficial. The next articles present the importance of costim ulatory signals in determining various types of immune responses, including autoim munity, and the role of regulatory T cells. Further, an interesting phenome non of epitope spreading as a mechanism for the progression of autoimmune diseases is presented. Codice articolo 9781402000379
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Autoimmunity
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Condizione: New. pp. 222 Index. Codice articolo 262177832
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Autoimmunity
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Hardcover. Condizione: Brand New. 1st edition. 207 pages. 9.75x6.50x0.25 inches. In Stock. Codice articolo x-1402000375
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