An Introduction to Bioinformatics is intended to be a complete study companion for the advanced undergraduate or beginning graduate student. It is self-contained in the sense that whatever the starting point may be, the reader will gain insight into bioinformatics. Underlying the work is the belief that bioinformatics is a kind of metaphoric lens through which the entire field of biology can be brought into focus, admittedly as yet imperfect, and understood in a unified way. Reflecting the highly incomplete present state of the field, emphasis is placed on the underlying fundamentals and acquisitions of a broad and comprehensive grasp of the field as a whole.
Bioinformatics is interpreted as the application of information science to biology, in which it plays a fundamental and all-pervasive role. This interpretation enables a remarkably unified view of the entire field of biology to be taken and hence offers an excellent entry point into the life sciences for those for whom biology is unfamiliar.
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Preface. 1. Introduction. I: Information. 2. The nature of information. 3. The transmission of information. 4. Sets and combinatorics. 5. Probability and likelihood. 6. Randomness and complexity. 7. Systems, networks and circuits. II: Biology. 8. Introduction to part II. 9. The nature of living things. 10. The molecules of life. III: Applications. 11. Introduction to part III. 12. Genomics. 13. Proteomics. 14. Interactions. 15. Metabolomics and metabonomics. 16. Medical applications. Bibliography.
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