Genes, Development, and Cancer: The Life and Work of Edward B. Lewis - Rilegato

Lewis, Edward B.; Lipshitz, Howard D.

 
9781402075919: Genes, Development, and Cancer: The Life and Work of Edward B. Lewis
Rilegato
ISBN 10: 140207591X ISBN 13: 9781402075919
Casa editrice: Kluwer Academic Pub, 2004

Sinossi

- For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume

- Papers are organized into sections that reflect the focus of the research

- Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Contenuti

Background -Invention of the cis-trans test for position effects -Position pseudoalleles -The bithorax pseudoalleles and the concept of developmental control -Gene evolution by tandem duplication -From cisvection to transvection- Extending the bithorax pseudoallelic series -Genetic versus functional models -From genes to gene complexes -Developmental genetics -Gain-of-function and loss-of-function alleles, and the operon model -Genetic mosaics: spatial and temporal aspects of bithorax function -The 1978 paper: a paradigm for the genetic control of development -Trans-acting regulators: positive and negative control of the homeotic complexes -Cis-regulation within the BX-C: the rules of engagement -Positional cloning of the BX-C -Completing the bithorax mutant series -The molecular basis of developmental control -Bithorax and the evolution of sexually dimorphic traits -DNA sequence motifs in the cis-regulatory regions of the BX-C -Evolution of the HOX complexes -Genetic and somatic effects of ionizing radiation -The political and social context -Leukemia and ionizing radiation -Political fallout -Thyroid radiation doses from weapons fallout -Best estimates of risk: leukemia in populations exposed to low doses of radiation -Estimates of lung cancer risk: the Batelle beagles

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Kluwer Academic Pub
Data di pubblicazione
2004
Lingua
Inglese
ISBN 10 
140207591X
ISBN 13 
9781402075919
Rilegatura
Copertina rigida
Numero di pagine
572
Contatto del produttore
non disponibile
Persona responsabile
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Germania

Altre edizioni note dello stesso titolo

9781461347460: Genes, Development and Cancer: The Life and Work of Edward B. Lewis

Edizione in evidenza

ISBN 10:  1461347467 ISBN 13:  9781461347460
Casa editrice: Springer Nature, 2012
Brossura