Effectively perform today's most effective, state-of-the-art neurosurgical procedures with Youmans Neurological Surgery, 6th Edition, edited by H. Richard Winn, MD. Still the cornerstone of unquestioned guidance on surgery of the nervous system, the new edition updates you on the most exciting developments in this ever-changing field. In print and online, it provides all the cutting-edge details you need to know about functional and restorative neurosurgery/deep brain stimulation, stem cell biology, radiological and nuclear imaging, neuro-oncology, and much more. And with nearly 100 intraoperative videos online at www.expertconsult.com, as well as thousands of full-color illustrations, this comprehensive, multimedia, 4-volume set remains the clinical neurosurgery reference you need to manage and avoid complications, overcome challenges, and maximize patient outcomes.
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"There is no doubt that Neurological Surgery is the grand dame of the major neurosurgical textbooks.and is recommended without hesitation."- JAMA, (review of 4th edition)
VOLUME 1
SECTION I Introduction to Neurological Surgery
PART 1
History
Chapter 1 Historical Overview of Neurosurgery
James Tait Goodrich and Eugene S. Flamm
PART 2
Basic Science
Chapter 2 Surgical Anatomy of the Brain
Hung Tzu Wen, Albert L. Rhoton Jr, and Antônio C. M. Mussi
Chapter 3 Molecular Biology Primer for Neurosurgeons
Kevin Y. Miyashiro and James Eberwine
Chapter 4 Neuroembryology
Harvey B. Sarnat, Laura Flores-Sarnat, and Joseph D. Pinter
Chapter 5 Stem Cell Biology in the Central Nervous System
Philip J. Horner and Samuel E. Nutt
Chapter 6 Neurons and Neuroglia
Bruce D. Trapp and Karl Herrup
Chapter 7 Cellular Mechanisms of Brain Energy Metabolism
Albert Gjedde and Pierre Magistretti
Chapter 8 Blood-Brain Barrier
Shahid M. Nimjee, Gerald A. Grant, H. Richard Winn, and Damir Janigro
Chapter 9 Cerebral Edema
Robert J. Weil and Edward H. Oldfield
Chapter 10 Physiology of the Cerebrospinal Fluid and Intracranial Pressure
?Anthony Marmarou and Andrew Beaumont
Chapter 11 Neurosurgical Epidemiology and Outcomes Assessment
Hugh Garton, Frederick G. Barker II, and Stephen J. Haines
parT 3
Approach To The Patient
Chapter 12 Altered Consciousness
Nicholas D. Schiff
Chapter 13 Neuroophthalmology
Timothy J. Martin and James J. Corbett
Chapter 14 Neurotology
P. Ashley Wackym and Christina L. Runge-Samuelson
Chapter 15 Neurourology
Brett D. Lebed and Eric S. Rovner
Chapter 16 Neuropsychological Testing
Jordan Grafman
parT 4
Radiologic Fundamentals
Chapter 17 Computed Tomography and Magnetic Resonance Imaging of the Brain
Thomas Aquinas Kim, Aleksandrs Uldis Kalnins, and Robert W. Prost
Chapter 18 Radiology of the Spine
Ajit Krishnaney and Michael T. Modic
Chapter 19 Physiologic Evaluation of the Brain with Magnetic Resonance Imaging
Amish H. Doshi, Pascal Bou-Haidar, and Bradley Delman
Chapter 20 Molecular Imaging of the Brain with Positron Emission Tomography
William P. Melega and Antonio A. F. De Salles
SECTION II General Neurosurgery
parT 1
Perioperative Care
Chapter 21 Neuroanesthesia: Preoperative Evaluation
Deepak Sharma and Arthur M. Lam
Chapter 22 Avoidance of Complications in Neurosurgery
Nirit Weiss and Kalmon D. Post
Chapter 23 Intracranial Pressure Monitoring
Vincent Y. Wang and Geoffrey T. Manley
Chapter 24 Principles of Neurocritical Care
Eelco F. M. Wijdicks and Alexander Y. Zubkov
parT 2
General Principles and Surgical Techniques
Chapter 25 Surgical Planning: Overview
Martin Weiss, Gabriel Zada, and Alexander A. Khalessi
Chapter 26 Positioning for Cranial Surgery
R. Webster Crowley, Aaron S. Dumont, M. Sean McKisic, and John A. Jane Sr
Chapter 27 Patient Positioning for Spinal Surgery
Peter D. Angevine, Paul R. Gigante, and Paul C. McCormick
Chapter 28 Positioning in Peripheral Nerve Surgery
Allen H. Maniker
Chapter 29 Incisions and Closures
Stirling Craig and John A. Persing
Chapter 30 Advantages and Limitations of Cranial Endoscopy
Jeroen R. Coppens and William T. Couldwell
Chapter 31 Thorascopic Spine Surgery
Rudolf Beisse
Chapter 32 Cranioplasty
Robert G. Whitmore, Shabbar F. Danish, and M. Sean Grady
parT 3
Geriatric Neurosurgery
Evaluation of Adult Hydrocephalus
Chapter 33 Production and Flow of Cerebrospinal Fluid
Conrad E. Johanson
Chapter 34 Clinical Evaluation of Adult Hydrocephalus
Nicole C. Keong, Marek Czosnyka, Zofia Czosnyka, and John D. Pickard
Management of Adult Hydrocephalus
Chapter 35 Shunting
Marvin Bergsneider and Eric Stiner
Chapter 36 Adult Hydrocephalus: The Role of Endoscopic Third Ventriculostomy
Jay Riva-Cambrin and James Drake
Subdural Hematomas
Chapter 37 Pathophysiology of Subdural Hematomas
Brent O'Neill, Jack Wilberger, and Adam Wilberger
Chapter 38 Medical and Surgical Management of Chronic Subdural Hematomas
Joachim K. Krauss, Lawrence F. Marshall, and Ralf Weigel
parT 4
Infection
Chapter 39 Basic Science of Central Nervous System Infections
Jeffrey M. Tessier and W. Michael Scheld
Chapter 40 Postoperative Infections of the Head and Brain
Christopher J. Farrell, Mary L. Pisculli, and Frederick G. Barker II
Chapter 41 Postoperative Infections of the Spine
Michael A. Finn and Meic H. Schmidt
Chapter 42 The Use and Misuse of Antibiotics in Neurosurgery
Koijan Kainth, Matthew A. Hunt, and Stephen J. Haines
Chapter 43 Brain Abscess
Allan R. Tunkel and W. Michael Scheld
Chapter 44 Meningitis and Encephalitis
Ian E. McCutcheon
Chapter 45 Acquired Immune Deficiency Syndrome
M. Kelly Nicholas, Rimas V. Lukas, and Koen van Besien
Chapter 46 Parasitic Infections
Oscar H. Del Brutto, Juan J. Figueroa, and Hector H. Garcia
Chapter 47 Surgical Risk of Transmittable Diseases
Donald E. Fry
SECTION III Epilepsy
parT 1
Basic Science of Epilepsy
Chapter 48 Epilepsy Surgery Overview
Guy M. McKhann II and Matthew A. Howard III
Chapter 49 Electrophysiologic Properties of the Mammalian Central Nervous System
Guy M. McKhann II and Damir Janigro
Chapter 50 Animal Models of Epilepsy
Maria Elisa Calcagnotto and Scott C.Baraban
Chapter 51 Malformations of Cortical Development
Gregory G. Heuer and Peter B. Crino
parT 2
Approach to the Patient
Chapter 52 Diagnosis and Classification of Seizures and Epilepsy
Frank Gilliam
Chapter 53 Antiepileptic Medications: Principles of Clinical Use
Blaise F. D. Bourgeois
parT 3
Preoperative Evaluation For Epilepsy
Chapter 54 Continuous Electroencephalography in Neurological-Neurosurgical Intensive Care: Applications and Value
Hiba Arif, Jan Claassen, and Lawrence J. Hirsch
Chapter 55 Neuroradiologic Evaluation for Epilepsy Surgery
Suzan Dyve, Leif Sørensen, Adam N. Mamelak, William W. Sutherling, and Gregory D. Cascino
Chapter 56 Evaluation of Patients for Epilepsy Surgery
Costas Michaelides, Garth Rees Cosgrove, and Andrew J. Cole
parT 4
Intraoperative Mapping and Monitoring for Cortical Resections
Chapter 57 Motor, Sensory, and Language Mapping and Monitoring for Cortical Resections
Ben Waldau and Michael M. Haglund
Chapter 58 Auditory Language Mapping
Zachary Wright and Guy M. McKhann II
Chapter 59 Investigation of Human Cognition in Epilepsy Surgery Patients
Hiroto Kawasaki and Chandan G. Reddy
parT 5
Specific Operative Approaches
Chapter 60 Intracranial Monitoring
Kenneth P. Vives, Andy J. Redmond, and Dennis D. Spencer
Chapter 61 Surgery for Extratemporal Lobe Epilepsy
James W. Leiphart and Itzhak Fried
Chapter 62 Standard Temporal Lobectomy
William Bingaman and Imad Najm
Chapter 63 Selective Amygdalohippocampectomy
Kim J. Burchiel, Andrew C. Zacest, and David Spencer
Chapter 64 Tailored Resections for Epilepsy
David W. Roberts
Chapter 65 Topectomy and Multiple Subpial Transection
Patrick J. Connolly, Atsushi Umemura, Gordon H. Baltuch, and Richard W. Byrne
Chapter 66 Hemispheric Disconnection Procedures
Johannes Schramm
Chapter 67 Vagus Nerve Stimulation for Intractable Epilepsy
James E. Baumgartner and Gretchen K. Von Allmen
Chapter 68 Radiosurgical Treatment of Epilepsy
Isaac Yang, Edward F. Chang, Nicholas M. Barbaro, Jean Régis, Marc Lévêque, Fabrice Bartolomei, and Patrick Chauvel
Chapter 69 Deep Brain Stimulation for Epilepsy
Robert S. Fisher, Brian Litt, and William C. Stacey
Chapter 70 Epilepsy Surgery: Outcome and Complications
Anthony L. Petraglia, Christian B. Kaufman, and Webster H. Pilcher
SECTION IV Functional Neurosurgery
parT 1
Overview
Chapter 71 Introduction
Andres M. Lozano and Ron L. Alterman
parT 2
Basic Science of Movement Disorders
Chapter 72 Anatomy and Synaptic Connectivity of the Basal Ganglia
Yoland Smith
Chapter 73 Rationale for Surgical Interventions in Movement Disorders
Thomas Wichmann and Mahlon R. DeLong
Chapter 74 Neuropathology of Movement Disorders
Kurt A. Jellinger
parT 3
Neurology of Movement Disorders
Chapter 75 Clinical Overview of Movement Disorders
Ihtsham ul Haq, Kelly D. Foote, and Michael S. Okun
Chapter 76 Patient Selection Criteria for Deep Brain Stimulation in Movement Disorders
Ioannis U. Isaias and Michele Tagliati
Chapter 77 Functional Imaging in Movement Disorders
David J. Brooks and Nicola Pavese
parT 4
Surgery for Movement Disorders
Chapter 78 Surgical Management of Tremor
Kazutaka Kobayashi, Jong Hyun Kim, William S. Anderson, and Frederick A. Lenz
Chapter 79 Pallidal Interventions for Parkinson's Disease
Philip A. Starr
Chapter 80 Subthalamic Deep Brain Stimulation for Parkinson's Disease
Alim Louis Benabid, John Mitrofanis, Stéphan Chabardés, Eric Seigneuret, Napoleon Torres, Brigitte Piallat, Abdelhamid Benazzouz, Valerie Fraix, Paul Krack, Pierre Pollak, Sylvie Grand, and Jean François LeBas
Chapter 81 Subthalamotomy in Parkinson's Disease: Indications and Outcome
Jorge Guridi, Lázaro Alvarez, Raul Macias, and José A. Obeso
Chapter 82 Deep Brain Stimulation for Dystonia
Ron L. Alterman
Chapter 83 Deep Brain Stimulation: Mechanisms of Action
Matthew D. Johnson, Cameron C. McIntyre, and Jerrold L. Vitek
Chapter 84 Emerging and Experimental Neurosurgical Treatments for Parkinson's Disease
Scellig Stone, Karim Mukhida, and Andres M. Lozano
Chapter 85 Selective Peripheral Denervation for Cervical Dystonia
Joachim K. Krauss
parT 5
Surgery for Psychiatric Disorders
Chapter 86 A History of Psychosurgery
Patrick M. Schweder and Garth Rees Cosgrove
Chapter 87 Surgery for Tourette's Syndrome
Robert J. Maciunas and Brian N. Maddux
Chapter 88 Surgery for Obsessive-Compulsive Disorder
Ali R. Rezai, Andre Machado, Donald A. Malone Jr, and Benjamin Greenberg
Chapter 89 Surgical Treatment of Major Depression
Clement Hamani, Brian Snyder, Adrian W. Laxton, Paul E. Holtzheimer, Helen S. Mayberg, and Andres M. Lozano
parT 6
Surgical Interventions for Spasticity
Chapter 90 Ablative Surgery for Spasticity
Marc Sindou and Patrick Mertens
Chapter 91 Management of Spasticity by Central Nervous System Infusion Techniques
Richard D. Penn and Daniel M. Corcos
parT 7
Miscellaneous
Chapter 92 Treatment of Intractable Vertigo
Zackary E. Boomsaad, Steven A. Telian, and Parag G. Patil
Chapter 93 Treatment Applications of Cortical Stimulation
Jay L. Shils and Jeffrey E. Arle
Chapter 94 Neuroprosthetics
Jacob A. Donoghue, Jacob H. Bagley, Gerhard M. Friehs, and Vasilios A. Zerris
VOLUME 2
SECTION V Oncology
parT 1
Overview
Chapter 95 Brain Tumors: General Considerations
Henry Brem, E. Antonio Chiocca, and Raymond Sawaya
parT 2
Basic Science of Neurooncology
Chapter 96 Brain Tumors: An Overview of Current Histopathologic Classifications
Gregory N. Fuller and Teresa Ribalta
Chapter 97 Brain Tumor Immunology and Immunotherapy
Roberta P. Glick, Terry Lichtor, and Amy B. Heimberger
Chapter 98 Brain Tumor Stem Cells
Hasan A. Zaidi, Francesco Di Meco, and Alfredo Quiñones-Hinojosa
Chapter 99 Proliferation Markers in the Evaluation of Gliomas
Tarik Tihan
Chapter 100 Molecular Genetics and the Development of Targets for Glioma Therapy
Nduka M. Amankulor and Eric C. Holland
Chapter 101 Growth Factors in Glial Tumors
Abhijit Guha and David Omahen
Chapter 102 The Genetic Origins of Brain Tumors
Gregory J. Riggins
Chapter 103 Invasion in Malignant Glioma
Ian Lee and Mark L. Rosenblum
Chapter 104 Angiogenesis and Brain Tumors: Molecular Targets and Molecular Scalpels
Steven Brem and Eric T. Wong
Chapter 105 Barriers to Delivery of Therapeutics to Brain Tumors
Dani S. Bidros, Michael A. Vogelbaum, and James K. C. Liu
Chapter 106 Epidemiology of Brain Tumors
James L. Fisher, Margaret Wrensch, Joseph L. Wiemels, and Judith A. Schwartzbaum
Chapter 107 Gene- and Viral-Based Therapies for Gliomas
Kaveh Asadi-Moghaddam and E. Antonio Chiocca
parT 3
Approach to the Patient
Chapter 108 Clinical Features: Neurology of Brain Tumor and Paraneoplastic Disorders
William R. Shapiro
Chapter 109 Radiologic Features of Central Nervous System Tumors
Michael A. Kraut, Nafi Aygun, and David M. Yousem
Chapter 110 Endovascular Techniques for Tumor Embolization
Robert Hirschl and Louis P. Caragine Jr
Chapter 111 Brain Tumors during Pregnancy
Alessandro Olivi, Mohamad Bydon, and Shaan M. Raza
Chapter 112 Principles of Chemotherapy
Karine Michaud and Susan M. Chang
Chapter 113 Brain Tumor Outcome Studies: Design and Interpretation
Frederick G. Barker II
Chapter 114 Frame and Frameless Stereotactic Brain Biopsy
Alessandro Olivi, Jon D. Weingart, Jason Liauw, and Shaan M. Raza
parT 4
Surgical Considerations
Chapter 115 Basic Principles of Cranial Surgery for Brain Tumors
Jon D. Weingart and Henry Brem
Chapter 116 Basic Principles of Skull Base Surgery
Madjid Samii, Marcos Tatagiba, and Venelin Gerganov
Chapter 117 Surgical Complications of Brain Tumors and Their Avoidance
Ronald E. Warnick
Chapter 118 Navigation for Brain Tumors
Gene H. Barnett
Chapter 119 Endoscopic Approaches to Brain Tumors
Peter Nakaji and Charles Teo
Chapter 120 Intraoperative Magnetic Resonance Imaging
Won Kim and Linda M. Liau
parT 5
Intrinsic Tumors
Chapter 121 Low-Grade Gliomas: Astrocytoma, Oligodendroglioma, and Mixed Glioma
Nader S...
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