Articoli correlati a Pharmaceutical Suspensions: From Formulation Development...

Pharmaceutical Suspensions: From Formulation Development to Manufacturing - Rilegato

 
9781441910868: Pharmaceutical Suspensions: From Formulation Development to Manufacturing

Sinossi

The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Informazioni sull?autore

ALOK K. KULSHRESHTHA, Ph.D., Associate Director, Pharmaceutical Technology at Alcon Research Ltd., Fort Worth, Texas, has 20 years of experience in the development of sterile ophthalmic, contact lens care, and dry eye products. During this tenure in pharmaceutical industry, Dr. Kulshreshtha has worked on several suspension drug products in different stages of development. Dr. Kulshreshtha’s interest in the suspension area started almost 30 years ago when he began his doctoral dissertation on  suspension rheology. Over the years, Dr. Kulshreshtha has worked on many new technologies for producing sterile suspensions. Dr. Kulshreshtha is the inventor/co-inventor of several Patents and has authored many peer reviewed publications. Dr. Kulshreshtha is a member of the American Association of Pharmaceutical Scientists (AAPS) and has been reviewer for AAPS abstracts screening for posters and symposia. Dr. Kulshreshtha holds a Ph.D. and M.S. in Chemical Engineering from Purdue University, and a Bachelor’s degree in Chemical Engineering from the Indian Institute of Technology, Kanpur, India.

ONKAR N. SINGH, Ph.D., M.B.A., Assistant Director, Development at Alcon Research Ltd., Fort Worth, Texas, has over 16 years of pharmaceutical product research and development of nasal, sterile ophthalmic, sterile otic, and parentral products. Dr. Singh is inventor/co-inventor of many patents related to formulations, process and formulation technology and has authored several peer reviewed articles. Prior to joining Alcon Inc., Dr. Singh was Manager at Access Pharmaceuticals, Dallas, Texas, leading efforts in the area of site specific targeted drug delivery systems for diagnostic and therapeutic areas of cancer therapy. At Access Pharmaceuticals, Dr. Singh worked on nanoparticles, liposomes, emulsion formulations, protein pharmaceuticals and gene delivery technology. Dr. Singh served as Secretary/Treasurer of the Ocular Focus Group of AAPS from 2002 to 2005 and has been a reviewer for AAPS abstracts, posters and symposia. Dr. Singh is a member of the American Association of Pharmaceutical Scientists (AAPS). Dr. Singh currently serves as an editorial board member of American Pharmaceutical Review Journal. Dr. Singh holds a B.S. in Pharmacy, M.S. in Pharmaceutics from Banaras Hindu University, India; Ph.D. in Pharmaceutics from University of Illinois at Chicago and M.B.A. from University of Texas at Arlington, Texas.

G. MICHAEL WALL, Ph.D., Senior Director of Pharmaceutical Products Development at Alcon Research, Ltd., Fort Worth, Texas, has over 21 years of pharmaceutical industrial experience in the development of intranasal, sterile ophthalmic and otic drug products. Dr. Wall is author or co-author of 2 patents and over 100 publications including peer-reviewed articles, abstracts, book chapters, book supplements and one book. Dr. Wall has led international, multidisciplinary teams in the development and approval of in the development and approval of Ciprodex® Sterile Otic Suspension and Patanase® Nasal Spray, as well as other products in countries around the world. Dr. Wall is a Scientific Fellow of the American Academy of Otolaryngology – Head and Neck Surgery. He has also served the American Chemical Society as a member for 30 years. Dr. Wall received a B.S. degree in chemistry from Auburn University, a M.S. degree in medicinal chemistry from Auburn University School of Pharmacy, a Ph.D. in medicinal chemistry from the University of Mississippi School of Pharmacy, and completed the Advanced Management Program (168th session) of the Harvard Business School.

Dalla quarta di copertina

Suspension dosage form is a preferred and widely accepted dosage forms for insoluble or poorly soluble drugs for various therapeutic applications. The suspension dosage form has long been used for insoluble and poorly soluble drugs for making oral, topical and parenteral products. Pharmaceutical Suspensions, From Formulation Development to Manufacturing provides the reader with a broad overview of suspension drug product technology. Individual chapters in this book focus on suspension formulation principles, excipients, analysis, pharmaceutical development, preclinical, clinical and regulatory aspects, as well as the emerging technology of nanosuspensions as nanomedicine. Various chapters in the book are written by authors from academia, regulatory agencies and industries who are experts in their respective fields. The book includes over 600 bibliographic citations, numerous tables and illustrations.

Pharmaceutical Suspensions is the only volume to date that systematically follows the suspension dosage development approach used widely in the pharmaceutical industries starting with pre-formulation/formulation development, pre-clinical evaluation and critical characterization method development, continuing to clinical trial essentials and ending with technology transfer essentials and regulatory filing guidance.

Pharmaceutical Suspensions, From Formulation Development to Manufacturing  provides a useful resource for pharmaceutical scientists, process scientists/engineers involved in the areas of research and development of pharmaceutical suspension dosage forms as well as for advanced pharmacy undergraduate and graduate students who want in-depth knowledge of suspension dosage form.

"Solid useful text on suspension formulation development"

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Compra usato

Condizioni: buono
Most items will be dispatched the...
Visualizza questo articolo

EUR 9,59 per la spedizione da Regno Unito a Italia

Destinazione, tempi e costi

EUR 9,70 per la spedizione da Germania a Italia

Destinazione, tempi e costi

Altre edizioni note dello stesso titolo

9781489984173: Pharmaceutical Suspensions: From Formulation Development to Manufacturing

Edizione in evidenza

ISBN 10:  1489984178 ISBN 13:  9781489984173
Casa editrice: Springer, 2014
Brossura

Risultati della ricerca per Pharmaceutical Suspensions: From Formulation Development...

Immagini fornite dal venditore

Editore: Springer, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Antico o usato Rilegato

Da: WeBuyBooks, Rossendale, LANCS, Regno Unito

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Condizione: Good. Most items will be dispatched the same or the next working day. A copy that has been read but remains in clean condition. All of the pages are intact and the cover is intact and the spine may show signs of wear. The book may have minor markings which are not specifically mentioned. Ex library copy with usual stamps & stickers. Codice articolo wbs8697764373

Contatta il venditore

Compra usato

EUR 50,30
Convertire valuta
Spese di spedizione: EUR 9,59
Da: Regno Unito a: Italia
Destinazione, tempi e costi

Quantità: 1 disponibili

Aggiungi al carrello

Immagini fornite dal venditore

Kulshreshtha, Alok K.|Singh, Onkar N.|Wall, G. Michael
Editore: Springer New York, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato
Print on Demand

Da: moluna, Greven, Germania

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by experienced experts in applicable field from academia/industry/regulatory agencies, volume will systematically discuss the development of stable pharmaceutical suspensionsALOK K. KULSHRESHTHA, Ph.D., Associate Direc. Codice articolo 4172180

Contatta il venditore

Compra nuovo

EUR 136,16
Convertire valuta
Spese di spedizione: EUR 9,70
Da: Germania a: Italia
Destinazione, tempi e costi

Quantità: Più di 20 disponibili

Aggiungi al carrello

Foto dell'editore

Kulshreshtha, Alok K.
Editore: Springer, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: Toscana Books, AUSTIN, TX, U.S.A.

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Hardcover. Condizione: new. Excellent Condition.Excels in customer satisfaction, prompt replies, and quality checks. Codice articolo Scanned1441910867

Contatta il venditore

Compra nuovo

EUR 125,47
Convertire valuta
Spese di spedizione: EUR 25,83
Da: U.S.A. a: Italia
Destinazione, tempi e costi

Quantità: 1 disponibili

Aggiungi al carrello

Immagini fornite dal venditore

Alok K. Kulshreshtha
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato
Print on Demand

Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system - poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle. 344 pp. Englisch. Codice articolo 9781441910868

Contatta il venditore

Compra nuovo

EUR 160,49
Convertire valuta
Spese di spedizione: EUR 11,00
Da: Germania a: Italia
Destinazione, tempi e costi

Quantità: 2 disponibili

Aggiungi al carrello

Immagini fornite dal venditore

Alok K. Kulshreshtha
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Buch. Condizione: Neu. Neuware -The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system ¿ poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch. Codice articolo 9781441910868

Contatta il venditore

Compra nuovo

EUR 160,49
Convertire valuta
Spese di spedizione: EUR 15,00
Da: Germania a: Italia
Destinazione, tempi e costi

Quantità: 2 disponibili

Aggiungi al carrello

Foto dell'editore

Editore: Springer, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: Ria Christie Collections, Uxbridge, Regno Unito

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Condizione: New. In. Codice articolo ria9781441910868_new

Contatta il venditore

Compra nuovo

EUR 168,14
Convertire valuta
Spese di spedizione: EUR 10,54
Da: Regno Unito a: Italia
Destinazione, tempi e costi

Quantità: Più di 20 disponibili

Aggiungi al carrello

Immagini fornite dal venditore

Alok K. Kulshreshtha
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: AHA-BUCH GmbH, Einbeck, Germania

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system - poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle. Codice articolo 9781441910868

Contatta il venditore

Compra nuovo

EUR 164,49
Convertire valuta
Spese di spedizione: EUR 14,99
Da: Germania a: Italia
Destinazione, tempi e costi

Quantità: 1 disponibili

Aggiungi al carrello

Foto dell'editore

Editore: Springer, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: California Books, Miami, FL, U.S.A.

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Condizione: New. Codice articolo I-9781441910868

Contatta il venditore

Compra nuovo

EUR 179,17
Convertire valuta
Spese di spedizione: EUR 7,75
Da: U.S.A. a: Italia
Destinazione, tempi e costi

Quantità: Più di 20 disponibili

Aggiungi al carrello

Foto dell'editore

Editore: Springer, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: Lucky's Textbooks, Dallas, TX, U.S.A.

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Condizione: New. Codice articolo ABLIING23Mar2411530293469

Contatta il venditore

Compra nuovo

EUR 158,34
Convertire valuta
Spese di spedizione: EUR 64,59
Da: U.S.A. a: Italia
Destinazione, tempi e costi

Quantità: Più di 20 disponibili

Aggiungi al carrello

Foto dell'editore

Kulshreshtha, Alok K. (Editor)/ Singh, Onkar N. (Editor)/ Wall, G. Michael (Editor)
Editore: Springer Verlag, 2009
ISBN 10: 1441910867 ISBN 13: 9781441910868
Nuovo Rilegato

Da: Revaluation Books, Exeter, Regno Unito

Valutazione del venditore 5 su 5 stelle 5 stelle, Maggiori informazioni sulle valutazioni dei venditori

Hardcover. Condizione: Brand New. 1st edition. 327 pages. 9.25x6.25x1.00 inches. In Stock. Codice articolo x-1441910867

Contatta il venditore

Compra nuovo

EUR 236,53
Convertire valuta
Spese di spedizione: EUR 11,72
Da: Regno Unito a: Italia
Destinazione, tempi e costi

Quantità: 2 disponibili

Aggiungi al carrello

Vedi altre 1 copie di questo libro

Vedi tutti i risultati per questo libro