Systems Analysis of Human Multigene Disorders: 799 - Rilegato

Libro 156 di 544: Advances in Experimental Medicine and Biology
 
9781461487777: Systems Analysis of Human Multigene Disorders: 799

Sinossi

Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.

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Contenuti

Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.

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9781493951949: Systems Analysis of Human Multigene Disorders: 799

Edizione in evidenza

ISBN 10:  1493951947 ISBN 13:  9781493951949
Casa editrice: Springer, 2017
Brossura