G Proteins, Cytoskeleton, and Cancer: 3 - Rilegato

Rilegato

ISBN 10: 1570595518 ISBN 13: 9781570595516

Casa editrice: R G Landes Co, 1998

Riassunto

Building upon the pioneering work of Klaus Weber, who in the 1970s discovered a key to the malignant transformation of normal cells by tumor virus infection or mutations via the disruption of actin cables and subsequent induction of membrane ruffling occurring with oncogenes such as v-Ras and v-Src, the global contributors aim toward the quantum leap of creating an anticancer Holy Grail that would attenuate the malignant activity of oncogenic mutants. The two dozen papers are organized under the four major headings of: actin-cytoskeleton, Ras/Rho family GTPases, links between G proteins and actin, and new anticancer drugs (e.g. farnesyltransferase inhibitors, SCH51344, and azatyrosine). Annotation c. by Book News, Inc., Portland, Or.

Dettagli dell?edizione

• Editore: R G Landes Co
• Data di pubblicazione: 1998
• Lingua: Inglese
• ISBN 10: 1570595518
• ISBN 13: 9781570595516
• Rilegatura: Copertina rigida
• Numero di pagine: 377
• Redattore: Maruta Hiroshi, Kohama Kazuhiro, Aktories K.
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile