Barriers and Channels Formed by Tight Junction Proteins II - Brossura

Brossura

ISBN 10: 1573318922 ISBN 13: 9781573318921

Casa editrice: Blackwell Pub, 2012

Riassunto

Tight junction proteins connect epithelial and endothelial cells and, importantly, form selective barriers and channels for paracellular transportation.  Two types of tight junction proteins—the claudin family (claudins-1 to -27) and the TAMP family (occludin, Marvel-D2, and tricellulin)—can be distinguished molecularly and functionally.  Recent work has focused on delineating the functional significance of differences in selective permeability, for example, by examining the regulatory mechanisms of tight junctions.  This work is of great clinical importance as many inflammatory or infectious diseases are characterized by increased permeability and the manipulation of tight junctions presents a new horizon in the development of novel therapeutics.  The volume Barriers and Channels Formed by Tight Junction Proteins II provides a detailed look at the recent advances in our understanding of tight junction regulation and dysregulation.  The papers included focus on three major themes: inflammation and gastrointestinal function; epithelial transport, barrier modulation, and food components; and tight junctions in intestinal and renal epithelia.

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Informazioni sull'autore

Michael Fromm is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley. Jörg-Dieter Schulzke is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley.

Dettagli dell'edizione

• Editore: Blackwell Pub
• Data di pubblicazione: 2012
• Lingua: Inglese
• ISBN 10: 1573318922
• ISBN 13: 9781573318921
• Rilegatura: Copertina flessibile
• Numero di pagine: 191
• Redattore: Fromm Michael, Schulzke Jorg-Dieter
• Contatto del produttore: non disponibile
• Persona responsabile: Wiley-VCH GmbH; product_safety@wiley.com; ; Boschstrasse 12; Weinheim; 69469; Germania