Sinossi
Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial.
After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals.
Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Informazioni sull?autore
Thomas D. Cook, David L. DeMets
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)
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Chapman and Hall/CRC, 2007
ISBN 10: 1584880279
ISBN 13: 9781584880271
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Introduction to Statistical Methods for Clinical Trials
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ISBN 10: 1584880279
ISBN 13: 9781584880271
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Condizione: Good. 1st Edition. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Codice articolo 39161315-6
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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)
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Chapman and Hall/CRC, 2007
ISBN 10: 1584880279
ISBN 13: 9781584880271
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An excellent copy. The pages are clean and unmarked. The binding is tight. Codice articolo pb16ismct
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Introduction to Statistical Methods for Clinical Trials
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Introduction to Statistical Methods for Clinical Trials (Hardcover)
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ISBN 10: 1584880279
ISBN 13: 9781584880271
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Hardcover. Condizione: new. Hardcover. Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial.After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials. Clinical trials have taken a prominent role in the research and approval of drugs. This text offers a summary of statistical design, including cross-over designs, sample size estimation, sequential methods for interim analyses, survival analysis, and repeated measures. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9781584880271
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Introduction to Statistical Methods for Clinical Trials (Chapman Hall/CRC Texts in Statistical Science)
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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)
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hardcover. Condizione: New. In shrink wrap. Looks like an interesting title! Codice articolo Q-1584880279
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