Targeting of Drugs: Strategies for Gene Constructs and Delivery: Vol 323 - Rilegato

NATO Advanced Study Institute On Targeting Of Drugs: Strategies For Gene Constructs And Delivery (1999 : Marathon, Greece)

 
9781586030094: Targeting of Drugs: Strategies for Gene Constructs and Delivery: Vol 323
Rilegato
ISBN 10: 1586030094 ISBN 13: 9781586030094
Casa editrice: Ios Pr Inc, 2006

Sinossi

Comprising the proceedings of the 10th NATO Advanced Studies Institute forum held in Marathon, Greece in June-July 1999, this volume contains 21 contributions addressing a variety of viral and non-viral vectors for the effective delivery of genes to target cells, the problems associated with such vectors, and methods of circumventing the problems. Written by academics and researchers in the fields of molecular genetics, gene therapy, experimental neurosurgery, tumor virology, molecular biology, pharmacology, and other fields, the contributions address such topics as adeno-associated viral vectors; overcoming barriers to nonviral gene delivery; plasmid gene delivery; liposomal DNA vaccines; progress towards third generation non-viral vectors for gene therapy; cationic amphiphiles as delivery system for genes into eukaryotic cells; design and properties of a lipid-based carrier system for systemic gene therapy; methacrylate-based polyplexes as transfection agent; and ligand-mediated gene delivery. Lacks a subject index. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Dalla quarta di copertina

Gene therapy, developed as an alternative to the use of therapeutic proteins, can be hampered by nuclease degradation of the plasmid DNA, its inability to access target cells or when within cells, to enter the nucleus and transfect these efficiently. This book deals with recent developments in circumventing the problems of direct plasmid administration by the use of viral or non-viral vectors. Representatives from both camps discuss the challenges and opportunities of the two approaches and present current progress with a variety of constructs. These include viruses such as retroviruses, lentiviruses, poxviruses, alphavirus, herpevirus and parvovirus. Non-viral constructs are represented by polycations, polymers, cationic liposomes and nanoparticles.

Dal risvolto di copertina interno

Gene therapy, developed as an alternative to the use of therapeutic proteins, can be hampered by nuclease degradation of the plasmid DNA, its inability to access target cells or when within cells, to enter the nucleus and transfect these efficiently. This book deals with recent developments in circumventing the problems of direct plasmid administration by the use of viral or non-viral vectors. Representatives from both camps discuss the challenges and opportunities of the two approaches and present current progress with a variety of constructs. These include viruses such as retroviruses, lentiviruses, poxviruses, alphavirus, herpevirus and parvovirus. Non-viral constructs are represented by polycations, polymers, cationic liposomes and nanoparticles.

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Ios Pr Inc
Data di pubblicazione
2006
Lingua
Inglese
ISBN 10 
1586030094
ISBN 13 
9781586030094
Rilegatura
Copertina rigida
Numero di pagine
277
Redattore
Gregoriadis Gregory, McCormack Brenda
Contatto del produttore
non disponibile
Persona responsabile
non disponibile

Altre edizioni note dello stesso titolo

9780306430237: Targeting of Drugs: Anatomical and Physiological Considerations: 155

Edizione in evidenza

ISBN 10:  0306430231 ISBN 13:  9780306430237
Casa editrice: Plenum Pub Corp, 1988
Rilegato