Essentials of Apoptosis: A Guide for Basic and Clinical Research - Rilegato

Rilegato

ISBN 10: 1588291464 ISBN 13: 9781588291462

Casa editrice: Humana Pr Inc, 2003

Riassunto

Basic and clinical investigators systematically compile a comprehensive but concise summary of essential, up-to-date information about apoptosis. The authors present the concepts, the molecular architecture, the biochemical pathways, and the pathophysiological significance of apoptosis. In addition, standard biochemical and cell biologic approaches to apoptosis research are described as a guideline for bench work, with clinical applications detailed for immune disorders, cancer, ischemia/reperfusion injury, and neuronal degeneration.

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Recensione

"...will be valuable to toxicologists, who need to understand the significance of the particular mechanisms of cell death." - BTS Newsletter

Contenuti

Part I: Molecules and Pathways of Apoptosis Caspases: Structure, Activation Pathways, and Substrates Brona M. Murphy and Seamus J. Martin Bcl-2 Family Proteins: Master Regulators of Apoptosis Xiao-Ming Yin, Wen-Xing Ding, and Yongge Zhao Inhibitors of Apoptosis Proteins Peter Liston, Wai Gin Fong, and Robert G. Korneluk Structural Biology of Programmed Cell Death Yigong Shi The Death Receptor Family and the Extrinsic Pathway Maria Eugenia Guicciardi and Gregory J. Gores The Mitochondrial Apoptosis Pathway Bruno Antonsson From Caspases to Alternative Cell-Death Mechanisms Marja Jäättelä and Marcel Leist Part II: Apoptosis in Action Apoptosis in Plants, Yeast, and Bacteria Ron Mittler and Vladimir Shulaev Programmed Cell Death in C. elegans Yi-Chun Wu and Ding Xue Cell Death in Drosophila Sujin Bao and Ross L. Cagan Cell Death in Mammalian Development Chia-Yi Kuan and Keisuke Kuida Apoptosis and Cancer: Pathogenic and Therapeutic Implications Sean L. O'Connor, Fermin Briones, Nikhil S. Chari, Song H. Cho, Rebecca L. Hamm, Yoshihiko Kadowaki, Sangjun Lee, Kevin B. Spurgers, and Timothy J. McDonnell Cell Death in Immune, Inflammatory, and Stress Responses J. John Cohen, Maria D. Devore, Mile Cikara, and Elizabeth A. Dowling Cell-Death Mechanisms in Neurodegenerative Diseases: Diversity Among Cerebral Ischemia, Parkinson's Disease, and Huntington's Disease R. Anne Stetler and Jun Chen Apoptosis in Ischemic Disease Zheng Dong and Manjeri A. Venkatachalam Part III: Approaches to the Study of Apoptosis Analysis of Apoptosis: Basic Principles and Procedures Li Bai, Jinzhao Wang, Xiao-Ming Yin, and Zheng Dong Index

Dettagli dell?edizione

• Editore: Humana Pr Inc
• Data di pubblicazione: 2003
• ISBN 10: 1588291464
• ISBN 13: 9781588291462
• Rilegatura: Copertina rigida
• Lingua: Inglese
• Numero edizione: 1
• Numero di pagine: 259
• Redattore: Yin Xiao-Ming, Dong Zheng