This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure.
This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
For forty years we have known the essential ingredients for protein folding an amino acid sequence, and water. But the problem of predicting the three-dimensional structure from its sequence has eluded computational biologists even in the age of supercomputers and high throughput structural genomics. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules, such as small ligands, nucleic acids or other proteins. Protein Structure Prediction focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well-known practitioners. Leaders in the field provide insights into template-based methods of prediction, structure alignment and indexing, protein features prediction, and methods for de novo structure prediction. Protein Structure Prediction is a cutting-edge text that all researchers in the field should have in their libraries.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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hardcover. Condizione: Good. Ex- library copy with stamps and stickers. Codice articolo mon0003287856
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Da: Basi6 International, Irving, TX, U.S.A.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. Codice articolo ABEJUNE24-194483
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Da: Basi6 International, Irving, TX, U.S.A.
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Da: Books Puddle, New York, NY, U.S.A.
Condizione: New. pp. 352 2nd Edition. Codice articolo 26291094
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Da: Majestic Books, Hounslow, Regno Unito
Condizione: New. pp. 352 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam. Codice articolo 7589577
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Da: Biblios, Frankfurt am main, HESSE, Germania
Condizione: New. pp. 352. Codice articolo 18291100
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Da: moluna, Greven, Germania
Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Describes cutting-edge techniques for prediction and accesses them from the perspective of their most well-known practitionersIncludes a comprehensive account of the history of protein structure predictionStep-by-step, readily reproducible . Codice articolo 4221704
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