Lipid Rafts: Properties, Controversies and Roles in Signal Transduction - Rilegato

Rilegato

ISBN 10: 1629489611 ISBN 13: 9781629489612

Casa editrice: Nova Science Pub Inc, 2014

Riassunto

For many years, the surface of cells was viewed as a homogeneous fluid lipid casing. However, it is now understood that the surface of cells is not homogeneous but instead contains domains selectively enriched in particular lipids and proteins. Although it is still not completely clear how these lipid platforms are formed, their existence provides a basis for the organisation of many cell processes. One possibility is that microdomain formation relies on lipid phase separation in the plane of the bilayer -- 'lipid raft' hypothesis. Lipid rafts are compelling since they provide spontaneous organisation for signal transduction as well as intracellular sorting and targeting. What are the functions of these domains? Do they rely on specific interactions and how do they change in response to cell signalling processes? Do they help in the understanding of cell signalling and immune function and how may they be disrupted in disease processes such as neurodegeneration?

Dettagli dell'edizione

• Editore: Nova Science Pub Inc
• Data di pubblicazione: 2014
• Lingua: Inglese
• ISBN 10: 1629489611
• ISBN 13: 9781629489612
• Rilegatura: Copertina rigida
• Numero di pagine: 269
• Redattore: Sillence Dan
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile