This second revised and updated edition is a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis, and presentation. Clinical Trials in Osteoporosis takes the user through the process step-by-step from start to finish. It also provides a background on regulatory guidelines, ethical implications, endpoints, current therapies, and the ideal drug to use. It will serve as a practical manual for clinicians and scientists new to the subject and provide a standard for existing centers to measure themselves against.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
The second revised and updated edition of Clinical Trials in Osteoporosis is a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis and presentation. It takes the user through the process step-by-step from start to finish, also providing a background on regulatory guidelines, ethical implications, endpoints, current therapies and the ideal drug to use.
Clinical Trials in Osteoporosis is intended to serve as a practical manual for clinicians and scientists coming to the subject new and to provide a standard for existing centers to measure themselves against.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Condizione: New. pp. 308. Codice articolo 18299693
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Condizione: New. pp. 308 2nd Edition. Codice articolo 26299687
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Da: Majestic Books, Hounslow, Regno Unito
Condizione: New. pp. 308 Illus. Codice articolo 7548280
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Da: CSG Onlinebuch GMBH, Darmstadt, Germania
soft cover. Condizione: Wie neu. Gebraucht - Wie neu -COLING. MILLER ANDDEREKPEARSON 1. 1. Why a Book about Clinical Trials in Osteoporosis There have been many books published about the design, conduct, and analysis of clinicaltrials. Whyareosteoporosistrialsaspecialcasethatdeserveabookoftheir own There are three main reasons. First, most diseases have a well-understood definitionandaetiology. Osteoporosisisadiseasethatisunderstoodbythosewo- ing within the subspecialty, but currently there is no definition that is agreeable to both medical and scientific communities and its aetiology is poorly understood. It is within this framework that the pharmaceutical industry is trying to develop new treatmentsfortheso-called'silentepidemic'. In layman's terms, the disease of osteoporosis is defined as 'brittle bones occurring in the elderly that could lead to fractures. 'The classical definition was 'a bony fracture caused by minimal trauma owing to a loss in bone mineral. ' A published consensus definition states that osteoporosis is 'a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to 1 fractures. ' The National Institutes of Health (NIH) Consensus Conference Statement on Osteoporosis Prevention, Diagnosis, and Therapy states that 'osteoporosis is a skeletal disorder characterized by compromised bone strength 2 predisposing to an increased risk of fracture. ' The World Health Organization (WHO) operationally defines osteoporosis as 'bone density 2. 5 standard dev- tions (SDs) below the mean for young white adult women at lumbar spine, 3 femoralneck,orforearm'. Itisnowrecommendedthatthediagnosticuseofthis 4 definition is restricted to bone density of the femur. Codice articolo 21953
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