Protein-Protein Complexes: Analysis, Modeling and Drug Design - Rilegato

Rilegato

ISBN 10: 184816338X ISBN 13: 9781848163386

Casa editrice: Imperial College Pr, 2010

Riassunto

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures)? How can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics?

The book consists of 13 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes, theory of protein-protein binding, prediction of interfaces and prediction of protein-protein complex structures. It serves as a bridge between analyzing protein-protein complexes and the prediction and design of interactions.

Dettagli dell'edizione

• Editore: Imperial College Pr
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 184816338X
• ISBN 13: 9781848163386
• Rilegatura: Copertina rigida
• Numero di pagine: 390
• Redattore: Zacharias Martin
• Contatto del produttore: non disponibile
• Persona responsabile: GPSR Kontakt; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Germania