Data Mining in Bioinformatics - Brossura
Libro 8 di 66: Advanced Information and Knowledge Processing
Sinossi
Provides systematic treatment of the application of data mining in bioinformatics, in a manner that is accessible to a computer-literate reader who understands the basics of genetics as well as to computationally interested biologists. Of particular interest to researchers in data mining and bioinformatics. The book is aimed at computer scientists, so necessary biology is explained as needed. Finally, problems are provided at the end of several chapters in case readers want to use the book as a text.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
Part I - Overview An Introduction to Data Mining in Bioinformatics A Survey of Bio-Data Analysis from Data Mining Perspective Part II - Sequence and Structure Alignment ANTICLUSTRAL: Multiple Sequence Alignment by Antipole Clustering RNA Structyre Comparison and Alignment Part III - Biological Data Mining Piecewise Constant Modeling of Sequential Data using Reversible Jump Markov Chain Monte Carlo Gene Mapping by Pattern Discovery Prediciting Protein Folding Pathways Data Mining Methods for a Systematics of Protein Subcellular Location Mining Chemical Compounds Part IV - Biological Data Managment Phyloinformatics: Towards a Phylogenetic Database Declarative and Efficinet Querying on Protein Secondary Sturctures Scalable Index Structures for Biological Data Glossary References Biographies Index
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Data Mining in Bioinformatics (eng)
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Data Mining in Bioinformatics
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunction ality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di erenttissues,its3Dstructureandactivesites,itsfunctionalandstruct ural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins remain in the cytoplasm after their synthesis and function as small factories catalyzing cellular metabolites. Other proteins that have a target signal in their sequences are directed to their target organelle (such as mitochondria) via posttranslational transport through the organelle membrane. Nuclear proteins are transferred through pores on the nuclear envelope to the nucleus and mostly function as regulators. The second major category of proteins is synthesized on endoplasmic reticulum(ER)-associated ribosomes and passes through the reticuloendothelial system, consisting of the ERand the Golgi apparatus. 352 pp. Englisch. Codice articolo 9781849968942
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. No known book on this areaFirst book containing the work of key researchers in biological data miningPresents new techniques on (a) gene expression data mining, (b) gene mapping for disease detection, and (c) phylogenetic knowledge discover. Codice articolo 4288958
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Data Mining in Bioinformatics (Advanced Information and Knowledge Processing)
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Taschenbuch. Condizione: Neu. Data Mining in Bioinformatics | Jason T. L. Wang (u. a.) | Taschenbuch | Advanced Information and Knowledge Processing | xii | Englisch | 2010 | Springer | EAN 9781849968942 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Codice articolo 107247748
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Provides systematic treatment of the application of data mining in bioinformatics, in a manner that is accessible to a computer-literate reader who understands the basics of genetics as well as to computationally interested biologists. Of particular interest to researchers in data mining and bioinformatics. The book is aimed at computer scientists, so necessary biology is explained as needed. Finally, problems are provided at the end of several chapters in case readers want to use the book as a text.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 352 pp. Englisch. Codice articolo 9781849968942
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - 8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunctionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di erenttissues,its3Dstructureandactivesites,itsfunctionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins remain in the cytoplasm after their synthesis and function as small factories catalyzing cellular metabolites. Other proteins that have a target signal in their sequences are directed to their target organelle (such as mitochondria) via posttranslational transport through the organelle membrane. Nuclear proteins are transferred through pores on the nuclear envelope to the nucleus and mostly function as regulators. The second major category of proteins is synthesized on endoplasmic reticulum(ER)-associated ribosomes and passes through the reticuloendothelial system, consisting of the ERand the Golgi apparatus. Codice articolo 9781849968942
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