This is a technically detailed, up-to-date clinical reference on all the newest developments in management of the menopause. The contents include chapters on every important topic in this field, ranging from aging for men to estrogens and the cardiovascular system in the over 60s. It also covers hormone replacement therapy (HRT) with chapters on the brain, the central nervous system, hemostasis, stroke, the bladder and breast epithelial proliferation plus chapters on the menopause and tibolone therapy, the lower urinary tract, sexual functioning, breast cancer, hormone related cancer, obesity, and leptin levels. Other chapters deal with assessment, contraindications, oral and transdermal HRT, monitoring, depression, the endometrium, skeletal effects, and bisphosphonates. Fully illustrated. Includes bibliographic references and index. Published annually.
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List of principal contributors. Introduction. Aging for men. Assessing well-being in menopausal women. Relative and absolute contraindications in hormone replacement therapy. Effects of oral and transdermal hormone replacement therapy in relation to serum estrogen levels. Continuation with hormone replacement therapy. Monitoring of women with hormone replacement therapy: what should we be doing? The place of tibilone in menopausal therapy. Selective estrogen receptor modulators: a review for the clinician. The molecular biology of the action of SERMs. When hormone replacement therapy is not possible. Hormone replacement therapy and the brain. Sex steroid hormones and the central nervous system: neuroendocrine effects of ?5 androgens in postmenopausal women. Depression, estrogen and neurotransmitters in the postmenopausal woman. Hormones and hemostasis. Changes in coronary arteries with estrogen therapy. Stroke, menopausal women and estrogen. The lower urinary tract in menopause: the contributions of aging and estrogen deficiency. Intravaginal estriol and the bladder. Menopause and sexual functioning. Sexuality and breast cancer: a review. Management of menopausal symptoms after breast cancer. Management of the menopause in women with hormone-related cancer. Progestogen and breast epithelial proliferation. Do progestogens adequately protect the endometrium? Interpretation of endometrial pathology with hormone replacement therapy in postmenopausal women. Obesity and the menopause. Leptin levels in the menopause. The skeletal effects of estrogen depletion and replacement: histomorphometric effects. Bisphosphonates. The role of initiating hormone replacement therapy to prevent and treat osteoporosis in the older postmenopausal woman. Estrogens and the cardiovascular system in the over 60's. Index.
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