Sinossi
Wnt signaling plays a critical role in development, normal physiology, and cancer. This book examines the biochemistry of Wnt signaling pathways, the developmental functions of Wnt ligands, and the role of Wnt signaling in cancer, particular colorectal cancer.
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Wnt Signaling (Cold Spring Harbor Perspectives in Biology)
Editore:
Cold Spring Harbor Laboratory Press, 2012
ISBN 10: 1936113236
ISBN 13: 9781936113231
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Da: killarneybooks, Inagh, CLARE, Irlanda
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Hardcover. Condizione: Near Fine. 1st Edition. Oversized hardcover, vii + 454 pages, NOT ex-library. Shipping weight over 1.2kg. Minor handling wear. Book is clean and bright with unmarked text, free of inscriptions and stamps, firmly bound. Issued without a dust jacket. Codice articolo 009374
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Wnt Signaling (Cold Spring Harbor Perspectives in Biology)
Editore:
Cold Spring Harbor Laboratory Pr, 2012
ISBN 10: 1936113236
ISBN 13: 9781936113231
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Da: HPB-Red, Dallas, TX, U.S.A.
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Hardcover. Condizione: Acceptable. Connecting readers with great books since 1972. Used textbooks may not include companion materials such as access codes, etc. May have condition issues including wear and notes/highlighting. We ship orders daily and Customer Service is our top priority! Codice articolo S_354105775
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Wnt Signaling
Editore:
Cold Spring Harbor Laboratory Press,U.S., US, 2012
ISBN 10: 1936113236
ISBN 13: 9781936113231
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Da: Rarewaves USA, OSWEGO, IL, U.S.A.
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Hardback. Condizione: New. Codice articolo LU-9781936113231
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Wnt Signaling (Cold Spring Harbor Perspectives in Biology)
Editore:
Cold Spring Harbor Perspective, 2012
ISBN 10: 1936113236
ISBN 13: 9781936113231
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Da: CSG Onlinebuch GMBH, Darmstadt, Germania
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Gebundene Ausgabe. Condizione: Wie neu. Gebraucht - Wie neu -Wnt proteins are signaling molecules that play critical roles during embryonic development and in the regeneration of adult tissues. They bind to Frizzled and LRP family receptors on the cell surface, triggering a series of events that cause -catenin to enter the nucleus and activate transcription factors that control cell fate and cell proliferation. Mutations in components of the Wnt pathway lead to developmental defects and are common in cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of canonical Wnt signaling, as well as -catenin-independent Wnt signaling and cross-talk with other pathways. The contributors examine the numerous Wnt ligands; their production, secretion, and interactions with components of the extracellular environment; and details of the downstream signaling pathways that mediate the effects of Wnt proteins on cells. The roles of Wnt signaling in stem cell self-renewal, cell polarity, body-axis specification, wound healing, and other aspects of normal development and physiology are also covered. This volume includes discussion of Wnt signaling in cancer, skeletal defects, neurological disorders, and other human disease states. Thus, it is an indispensable reference for cell and developmental biologists as well as those, especially in the fields of stem cell biology and regenerative medicine, who are interested in targeting the Wnt pathway for therapeutic purposes. Codice articolo 43320
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Wnt Signaling
Editore:
Cold Spring Harbor Laboratory Press,U.S., US, 2012
ISBN 10: 1936113236
ISBN 13: 9781936113231
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Da: Rarewaves USA United, OSWEGO, IL, U.S.A.
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Hardback. Condizione: New. Codice articolo LU-9781936113231
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