Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression - Brossura

Barrett, Lucy W.

Brossura

ISBN 10: 3034806787 ISBN 13: 9783034806787

Casa editrice: Springer, 2013

Riassunto

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as junk DNA , it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5 and 3 untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.?

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Contenuti

Introduction.- Promoter.- 5’ Untranslated Region.- Structure.- Intronic Regions.- 3’ Untranslated Region.- Non-coding RNAs.- Conclusion.

Dettagli dell'edizione

• Editore: Springer
• Data di pubblicazione: 2013
• Lingua: Inglese
• ISBN 10: 3034806787
• ISBN 13: 9783034806787
• Rilegatura: Copertina flessibile
• Numero edizione: 1
• Numero di pagine: 64
• Contatto del produttore: non disponibile
• Persona responsabile: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Germania