Vascular Adhesion Molecules and Inflammation - Brossura

Brossura

ISBN 10: 3034897537 ISBN 13: 9783034897532

Casa editrice: Birkhäuser, 2012

Riassunto

The book will provide an overview of the roles of vascular adhesion molecules in health and disease, with chapters on their cell biology, followed by chapters reviewing their importance in specific disease processes. Vascular adhesion molecules are vital for the physiological processes of leukocyte trafficking and also critically involved in the enhanced leukocyte emigration that is a key feature of all inflammatory and immune diseases. The book is designed to provide up-to-date, linked reviews of the subject suitable for postgraduate students entering the field or research workers from allied disciplines needing a modern overview.

Su questo libro

Contenuti

How early studies of inflammation led to our current views on the roles of vascular adhesion molecules.- Adhesion of leukocytes from flow: The selectins and their ligands.- Co-operative signaling between leukocytes and endothelium mediating firm attachment.- Production and presentation of chemokines by endothelial cells.- Platelet-activating factor: A signaling molecule for leukocyte adhesion.- Tight junctions and adherens junctions in endothelial cells: Structure and regulation.- The role of PECAM in leukocyte emigration.- Selective lymphocyte migration into secondary lymphoid rrgans and inflamed tissues.- Oxidation-reduction sensitive regulation of vascular inflammatory gene expression.- Quantification and imaging of vascular adhesion molecule expression in inflammatory diseases in vivo.- Leukocyte adhesion and activation in xenografts.- Control of leukocyte adhesion and activation in ischemia-reperfusion injury.- Control of leukocyte adhesion and activation in atherogenesis.

Dettagli dell?edizione

• Editore: Birkhäuser
• Data di pubblicazione: 2012
• ISBN 10: 3034897537
• ISBN 13: 9783034897532
• Rilegatura: Copertina flessibile
• Lingua: Inglese
• Numero di pagine: 276
• Redattore: Pearson Jeremy D.
• Contatto del produttore: non disponibile