Multicomponent Reactions - Rilegato

Rilegato

ISBN 10: 3527308067 ISBN 13: 9783527308064

Casa editrice: Vch Verlagsgesellschaft Mbh, 2005

In the very first book on this hot topic, the expert editors and authors present a comprehensive overview of these elegant reactions.

From the contents:

Organoboron compounds
Free-radical mediated multicomponent coupling reactions
Applications in drug discovery
Metal catalyzed reactions
Total synthesis of natural products
Asymmetric isocyanide-based reactions
The Biginelli reaction
Asymmetric isocyanide-based reactions
The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and related transformations
Catalytic asymmetric reactions
Algorithm based methods for discovering novel reactions
Post-condensation modifications of the Passerini and Ugi reactions

An essential reference for organic and catalytic chemists, and those working in organometallics both in academia and industry.

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Recensione:

"...it will be useful to the specialists in the field. Naturally, librarians may also like to acquire this book."
Angewandte Chemie

"Das Buch hat mich sehr positiv �berrascht. Gerade die Vielfalt an beschriebenen Methoden und indirekt an m�glichen Zielstrukturen machen >Multicomponent Reactions< zu einem unverzichtbaren Werkzeug f�r Anwender, welche in der Parallelchemie arbeiten."
www.organische-chemie.ch

"Fortgeschrittene, die sich f�r MCR interessieren oder auf diesem Gebiet arbeiten, werden in diesem Buch eine Quelle der Inspiration finden."
Nachrichten aus der Chemie

"....ist diese erste Monographie �ber Multikomponentenreaktionen f�r Spezialisten auf dem Gebiet recht n�tzlich, und selbstverst�ndlich sollten auch Bibliotheken eine Anschaffung ins Auge fassen."
Angewandte Chemie

L'autore:

Jieping Zhu received his BSc from Hanzhou Normal University in 1984 and his MSc from Lanzhou University in 1987 under Professor Y. -L. Li. In 1991, he obtained his PhD from the Universit� Paris XI under Professor H. -P. Husson. After 18 months post-doctoral research with Professor Sir D. H. R. Barton at Texas A & M University in USA, he joined the Institut de Chimie des Substances Naturelles (CNRS) in December 1992, where he is currently Director of Research. His main research interests center on the development of novel synthetic methods, their application in the synthesis of bioactive natural products, and the design of novel multicomponent reactions.
Dr. Zhu has published over 110 research papers.
Hugues Bienaym� gained his PhD in organic chemistry at the university of Paris under Professor A. Lubineau, than took up a post-doctoral position at the University of Geneva under the supervision of Professor W. Oppolzer. He joined Rh�ne-Poulenc (Aventis) in 1991 where he held various research positions in process and discovery chemistry. From 1995 to 2000 he was head of the combinatorial and discovery chemistry group for the company's central research department, developing multi-component condensations as a general tool to accelerate drug discovery. In 1996 the company awarded him the title "associate professor".
In 2001, Dr. Bienaym� founded Chrysalon, a start-up in the field of combinatorial chemistry. After the company's merger in 2003, he became managing director and CSO of Urogene, a biotech company dedicated to discovering new drugs in urology.
Hugues Bienaym� is the author or co-author of more than 40 publications and patents.

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