Articoli correlati a Transgenic Models in Pharmacology: 159
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Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
Preface.- Part 1: Transgenic Techniques.-1. Novel mouse models in biomedical research: The power of dissecting pathways by quantitative control of gene activities.- Part 2: Molecular Systems.- 2. Adrenergic System. 3. Muscarinic Acetylcholine Receptor Knockout Mice. 4. Mouse Models of NO/ Natriuretic Peptide/ cGMP Kinase Signaling. 5. Transgenic Models for the Study of Protein Kinase A-regulated Signal Transduction. 6. G-Protein-Mediated Signalling Pathways. 7. Analysis of Integrin Function by Gene Targeting in Mice. Part 3: Nervous System.- 8. Transgenic Mouse Models in the Analysis of Neurotransmitter Release Mechanisms. 9. Analysis of GABA receptor assembly and function in targeted mutant mice. 10. Neurotrophic Factors. 11.Genetic Analysis of the Endogenous Opioid System.- Part 4: Cardiovascular System.- 12. Transgenic Mouse Models of Cardiovascular Function and Disease. 13. Renin-Angiontensin-System/Blood Pressure Control. 14. Lipoprotein Transport.- Part 5: Immunology/Hematology/Inflammation.- 15. Transgenic Animals of Enzymes and Receptors in Prostanoid Synthesis and Actions; Phenotypes and Implications in Drug Development. 16. Coagulation and Fibrinolysis in Genetic Modified Mice. 17. Transgenic Animals in Primary Hemostasis and Thrombosis. 18. Chemokine Receptors.- Part 6: Endocrinology.- 19. Steroid Receptors. 20. Reproductive System.- Part 7: Toxicology.- 21. Understanding Molecular Mechanism of Toxicity and Carcinogenicity Using Gene Knockout and Transgenic Mouse Models.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Transgenic Models in Pharmacology (Handbook of Experimental Pharmacology, 159)
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Transgenic Models in Pharmacology
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Transgenic models in pharmacology : [with 42 tables] contributors M. Bader . Ed. Stefan Offermanns and Lutz Hein
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. with contributions by numerous expertsUp-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives a. Codice articolo 4876962
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Transgenic Models in Pharmacology
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The aim of this volumeis to give up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes.This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects. Codice articolo 9783540001096
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Transgenic Models in Pharmacology
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The aim of this volume is to give up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 684 pp. Englisch. Codice articolo 9783540001096
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