Since 1958 the Association for the Study of Internal Fixation (ASIF) has worked to establish the experimental and biomechanical prin- ciples of the operative treatment of fractures. It has been proven that immediate, pain-free mobilization, made possible by stable internal fixation, is the key to restoring function in a fractured extremity. The same principles were applied in 1972173 by Roland Schmoker, who developed a universal plate and sophisticated instrument set designed initially for the treatment of comminuted fractures of the mandible. To extend the applications of his plate to reconstructions after ex- tensive tumor resections, he supplemented the device with tem- poromandibular joint prostheses and anchoring elements for the at- tachment of dentures. He first tested the functional stability of these implants experimentally in sheep. Later he found that the minipig had a more human-like jaw shape and masticatory action, and so he tested the implants in 37 mini pigs that underwent extensive mandibular re- sections without bone grafting, using sequential dye injections and postoperative weight gain to chart the progress of osseous regener- ation. Seven other animals were not operated and served as controls.
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1 Historical Review.- 2 Evaluation of Preexisting Methods.- 3 Statement of Problem.- I: Experimental Studies.- Materials and Methods.- 1 Implants.- 1.1 Mandibular Reconstruction Plate.- 1.2 Condylar Prosthesis.- 1.3 Reconstruction Plate with Condylar Head.- 1.4 Anchoring Element for Abutments.- 2 Animal Experiments.- 2.1 Experimental Animal.- 2.2 Experimental Design.- 2.3 Operating Technique.- 2.4 Postoperative Follow-Ups.- 2.5 Necropsy.- 2.6 Technique of Examination.- Results.- Discussion.- 1 Discussion of the Method.- 2 Discussion of Results.- 3 Clinical Significance.- II: Clinical Application.- Materials, Methods, and Results.- Discussion.- Conclusions.- Acknowledgments.- References.
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