Sinossi
This is an overview of the advantages and disadvantages of the different methods currently available for the assessment of cell proliferation. Researchers involved with each method critically review the techniques and discuss how their particular techniques may be applied to clinical material.
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Contenuti
Contents: Regulation of the Eukaryotic Cell Cycle.- Growth Factors, Oncogenes and Tumour Suppressor Genes.- The Kinetic Organisation of Tissues.- Basic Methods for Assessing Cellular Proliferation.- Mitosis Counting.- Flow Cytometry.- Measurement of Cell Proliferation Using Bromodeoxyuridine.- The Application of ImmunohistoChemistry in Assessment of Cellular Proliferation.- Nucleolar Organiser Regions.- Clinical Aspects of Assessing Cell Proliferation.- Cell Proliferation and the Principles of Cancer Chemotherapy.- Subject Index.
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